Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 10/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 10/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 5/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4590799 | 0.92 | RAB9A (0.44) | NPC1RAB9ACYP4F2CYP4A11MLNR | |
| SCHEMBL4590822 | 0.80 | RAB9A (0.47) | NPC1RAB9APDK2 | |
| SCHEMBL4598133 | 0.79 | PLA2G7 (0.39) | NPC1RAB9AWNT3APDK2 | |
| Trifluoroacetic Acid SCHEMBL3182204 | 0.79 | ALOX5AP (0.43) | NPC1RAB9ACYP4F2CYP4A11 | |
| SCHEMBL4590531 | 0.78 | RAB9A (0.63) | NPC1RAB9A | |
| SCHEMBL4589979 | 0.75 | NPC1 (0.43) | NPC1RAB9ACYP4F2CYP4A11 | |
| SCHEMBL4590863 | 0.74 | CYP11B1 (0.46) | NPC1MLNR | |
| SCHEMBL4590767 | 0.74 | PDK2 (0.47) | NPC1RAB9APDK2 | |
| Trifluoroacetic Acid SCHEMBL3169886 | 0.73 | PDK2 (0.51) | NPC1RAB9APDK2 | |
| SCHEMBL4590673 | 0.72 | PDK2 (0.52) | NPC1RAB9APDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899321-A1 | HETEROARYL-SUBSTITUTED AMIDES COMPRISING A SATURATED LINKER GROUP, AND THEIR USE AS PHARMACEUTICALS | Sanofi-Aventis (FR) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007000246-A1 | HETEROARYL-SUBSTITUTED AMIDES COMPRISING A SATURATED LINKER GROUP, AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (DE) | 2007-01-04 | — | — | WO | disclosed |