Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 11/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4598130 | 0.79 | NPC1 (0.38) | RAB9ANPC1PDK2WNT3A | |
| SCHEMBL4590822 | 0.79 | RAB9A (0.47) | PLA2G7RAB9ANPC1PDK2IL4I1 | |
| SCHEMBL4590531 | 0.76 | RAB9A (0.63) | RAB9ANPC1HPGDNPSR1 | |
| SCHEMBL4590799 | 0.76 | RAB9A (0.44) | PLA2G7RAB9ANPC1IL4I1HPGD | |
| SCHEMBL4590767 | 0.73 | PDK2 (0.47) | PLA2G7RAB9ANPC1PDK2 | |
| SCHEMBL3182212 | 0.71 | NPC1 (0.39) | RAB9ANPC1PDK2WNT3AHPGD | |
| SCHEMBL4590673 | 0.70 | PDK2 (0.52) | RAB9ANPC1PDK2IL4I1 | |
| SCHEMBL4590073 | 0.70 | MTNR1A (0.55) | RAB9ANPC1PDK2HPGD | |
| SCHEMBL4590077 | 0.70 | RAB9A (0.41) | RAB9ANPC1PDK2HPGDNPSR1 | |
| SCHEMBL12020957 | 0.69 | NPC1 (0.52) | RAB9ANPC1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899321-A1 | HETEROARYL-SUBSTITUTED AMIDES COMPRISING A SATURATED LINKER GROUP, AND THEIR USE AS PHARMACEUTICALS | Sanofi-Aventis (FR) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007000246-A1 | HETEROARYL-SUBSTITUTED AMIDES COMPRISING A SATURATED LINKER GROUP, AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (DE) | 2007-01-04 | — | — | WO | disclosed |