SCHEMBL459823

SCHEMBL459823

CCOC(=O)NN=C=N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL472886 0.81
SCHEMBL8158146 0.79
SCHEMBL14492119 0.76
SCHEMBL8968079 0.75 ALOX15 (0.40)
SCHEMBL9644530 0.73
SCHEMBL10663041 0.71
SCHEMBL16870404 0.71
SCHEMBL208478 0.71
Vinyl Ether SCHEMBL8968429 0.71 GAA (0.40)
Methacrylic Acid SCHEMBL10867682 0.71 RAB9A (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104829843-B A kind of citric acid and chitin modified Biocompatible Polyurethane and preparation method thereof 中南大学 2017-06-30 CN disclosed
EP-2801376-A1 Methods of performing medical procedures that promote bone growth, methods of making compositions that promote bone growth, and apparatus for use in such methods Doctor's Research Group, Inc. (US) 2014-11-12 EP disclosed
US-8211458-B2 Methods of performing medical procedures that promote bone growth, methods of making compositions that promote bone growth, and apparatus for use in such methods DOCTOR'S RESEARCH GROUP, INC. (US) 2012-07-03 US disclosed
US-20120065424-A1 LOW-CATALYST CARBODIIMIDE GROUPS AND/OR ISOCYANATE MIXTURES COMPRISING URETONIMINE GROUPS EVONIK DEGUSSA GMBH (DE) 2012-03-15 US disclosed
US-20110274645-A1 Methods of performing medical procedures that promote bone growth, methods of making compositions that promote bone growth, and apparatus for use in such methods Doctor's Research Group, Inc., a Connecticut Corporation 2011-11-10 US disclosed
US-7964207-B2 Methods of performing medical procedures that promote bone growth, method of making compositions that promote bone growth, and apparatus for use in such methods DOCTOR'S RESEARCH GROUP, INC. (US) 2011-06-21 US disclosed
EP-1789088-A2 METHODS OF PERFORMING MEDICAL PROCEDURES THAT PROMOTE BONE GROWTH, METHODS OF MAKING COMPOSITIONS THAT PROMOTE BONE GROWTH, AND APPARATUS FOR USE IN SUCH METHODS Doctor's Research Group, Inc. (US) 2007-05-30 EP disclosed
US-20060194939-A1 Aqueous dispersions consisting of polycarbodiimides BASF AKTIENGESELLSCHAFT (DE) 2006-08-31 US disclosed
WO-2005094553-A2 COMPOSITIONS FOR PROMOTING BONE GROWTH AND METHODS THEREOF DOCTOR'S RESEARCH GROUP, INC. (US) 2005-10-13 WO disclosed
US-20050220771-A1 Reacting a naturally occurring polyol and a biocompatible, synthetic polyol and isocyanate which react to form a polyesterurethane; composition promotes bone growth when positioned in the vicinity of a bone of a mammal; use of multicompartment sealed container DOCTOR'S RESEARCH GROUP, INC. 2005-10-06 US disclosed
US-4668726-A Cationic and non-ionic fluorochemicals and fibrous substrates treated therewith MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-05-26 US disclosed
EP-0084220-B1 CELLULAR PRESSURE-SENSITIVE ADHESIVE PRODUCT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-01-07 EP disclosed
US-4566981-A OIL AND WATER REPELLENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-01-28 US disclosed
EP-0160402-A2 Fluorochemicals and fibrous substrates treated therewith MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-11-06 EP disclosed
US-4440705-A FROM POLYETHER POLYOLS WITH TERMINAL HYDROXYETHYLENE GROUPS BASF AKTIENGESELLSCHAFT (DE) 1984-04-03 US disclosed
US-4415615-A FOAMING, COATING ON BAKCING, AND IN SITU POLYMERIZATION MINNESOTA MINING AND MANUFACTURING CO. (US) 1983-11-15 US disclosed
EP-0084220-A1 Cellular pressure-sensitive adhesive product MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-07-27 EP disclosed
US-4266040-A Polyazlactone-electron deficient ethylenically unsaturated resinous compositions and method for foaming same DESOTO, INC. (US) 1981-05-05 US disclosed
US-4055522-A AROMATIC ALDEHYDE, TRIMERIZATION CATALYST MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1977-10-25 US disclosed
US-4024090-A Process for molding polyurethane foams BAYER AKTIENGESELLSCHAFT (DT) 1977-05-17 US disclosed