Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CAD | P27708 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8158146 | 0.79 | — | — | |
| SCHEMBL472886 | 0.76 | — | — | |
| SCHEMBL16384675 | 0.76 | GAA (0.36) | ALOX15GAACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL459823 | 0.75 | — | — | |
| Urethane SCHEMBL7112256 | 0.74 | ALOX15 (0.56) | ALOX15GAACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL28349630 | 0.72 | ALOX15 (0.46) | ALOX15GAACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL8475744 | 0.69 | ALOX15 (0.43) | ALOX15GAACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL32131 | 0.69 | ALOX15 (0.52) | ALOX15GAACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL9644530 | 0.69 | — | — | |
| SCHEMBL420598 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500214-B1 | Process for preparing foams | ICI PLC (GB) | 1996-02-28 | — | — | EP | disclosed |
| EP-0403066-B1 | C02 blown integral skin foams | ICI PLC (GB) | 1994-08-03 | — | — | EP | disclosed |
| US-5234960-A | PROCESS FOR PREPARING FOAMS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-08-10 | — | — | US | disclosed |
| EP-0500214-A2 | Process for preparing foams | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-08-26 | — | — | EP | disclosed |
| US-5071881-A | Reacting an organic polyisocyanate, an isocyanate reactive composition and an inert blowing agent | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-12-10 | — | — | US | disclosed |
| EP-0403066-A2 | C02 blown integral skin foams | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-12-19 | — | — | EP | disclosed |