Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | GFER | P55789 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13921817 | 0.89 | KCNH3 (0.65) | ALDH1A1CYP3A4MEN1KMT2AMAPT | |
| SCHEMBL1085867 | 0.88 | MEN1 (0.71) | MEN1KMT2AMAPTGAAGFER | |
| SCHEMBL6051261 | 0.87 | NR4A1 (0.67) | ALDH1A1CYP3A4MEN1KMT2AMAPT | |
| SCHEMBL4598738 | 0.87 | NR4A1 (0.67) | ALDH1A1CYP3A4MEN1KMT2AMAPT | |
| SCHEMBL13302353 | 0.86 | MEN1 (0.69) | MEN1KMT2AMAPTGAAGFER | |
| SCHEMBL1921496 | 0.84 | MTNR1B (0.72) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL917608 | 0.82 | MTNR1B (0.65) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL30080139 | 0.82 | MTNR1B (0.65) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL13921885 | 0.82 | KCNH3 (0.58) | ALDH1A1CYP3A4MEN1KMT2AMAPT | |
| SCHEMBL29371962 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100544701-C | Hair colouring compositions based on diaminopyrazole compounds | PROCTER & GAMBLE (US) | 2009-09-30 | — | — | CN | claimed |
| EP-1480605-B1 | HAIR COLORING COMPOSITIONS BASED ON DIAMINOPYRAZOLE COMPOUNDS | PROCTER & GAMBLE (US) | 2008-04-09 | — | — | EP | claimed |
| CN-101137345-A | Novel hair coloring compositions for oxidative hair dyeing | PROCTER & GAMBLE (US) | 2008-03-05 | — | — | CN | claimed |
| US-7303592-B2 | Hair coloring compositions for use in oxidative hair dyeing | THE PROCTER & GAMBLE COMPANY (US) | 2007-12-04 | — | — | US | claimed |
| EP-1855644-A2 | HAIR COLORING COMPOSITIONS FOR USE IN OXIDATIVE HAIR DYEING | The Procter and Gamble Company (US) | 2007-11-21 | — | — | EP | claimed |
| WO-2006099115-A2 | HAIR COLORING COMPOSITIONS FOR USE IN OXIDATIVE HAIR DYEING | THE PROCTER & GAMBLE COMPANY (US) | 2006-09-21 | — | — | WO | claimed |
| CN-1678283-A | Hair coloring compositions based on diaminopyrazole compounds | PROCTER & GAMBLE (US) | 2005-10-05 | — | — | CN | claimed |
| US-20050188480-A1 | Novel hair coloring compositions for use in oxidative hair dyeing | WELLA OPERATIONS US, LLC | 2005-09-01 | — | — | US | claimed |
| US-6887280-B2 | Hair coloring compositions for use in oxidative hair dyeing | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-03 | — | — | US | claimed |
| EP-1480605-A1 | HAIR COLORING COMPOSITIONS BASED ON DIAMINOPYRAZOLE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2004-12-01 | — | — | EP | claimed |
| US-20030196280-A1 | Novel hair coloring compositions for use in oxidative hair dyeing | WELLA OPERATIONS US, LLC | 2003-10-23 | — | — | US | claimed |
| WO-2003075872-A1 | HAIR COLORING COMPOSITIONS BASED ON DIAMINOPYRAZOLE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2003-09-18 | — | — | WO | claimed |
| US-11714080-B2 | Compounds and methods of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC (US) | 2023-08-01 | — | — | US | disclosed |
| US-11692998-B2 | Compounds and methods of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC (US) | 2023-07-04 | — | — | US | disclosed |
| US-20210215670-A1 | COMPOUNDS AND METHODS OF IDENTIFYING, SYNTHESIZING, OPTIMIZING AND PROFILING PROTEIN MODULATORS | HMI Medical Innovations, LLC | 2021-07-15 | — | — | US | disclosed |
| US-20210215671-A1 | COMPOUNDS AND METHODS OF IDENTIFYING, SYNTHESIZING, OPTIMIZING AND PROFILING PROTEIN MODULATORS | HMI Medical Innovations, LLC | 2021-07-15 | — | — | US | disclosed |
| US-6887280-B2 | Hair coloring compositions for use in oxidative hair dyeing | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-03 | — | — | US | disclosed |
| EP-1480605-A1 | HAIR COLORING COMPOSITIONS BASED ON DIAMINOPYRAZOLE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2004-12-01 | — | — | EP | disclosed |
| US-20030196280-A1 | Novel hair coloring compositions for use in oxidative hair dyeing | WELLA OPERATIONS US, LLC | 2003-10-23 | — | — | US | disclosed |
| WO-2003075872-A1 | HAIR COLORING COMPOSITIONS BASED ON DIAMINOPYRAZOLE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2003-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030196280-A1 | Novel hair coloring compositions for use in oxidative hair dyeing | CBR1, CBR3, CYC1 | ALDH1A1 9/4885CYP3A4 290/4885MEN1 4596/4885 |
| US-20050188480-A1 | Novel hair coloring compositions for use in oxidative hair dyeing | COXFA4L2, TYR, GPX4 | ALDH1A1 89/4885CYP3A4 310/4885MEN1 4338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.