Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28491605 | 0.77 | TSHR (0.46) | ALOX15SMN1; SMN2TSHRTDP1TRPV1 | |
| SCHEMBL28528169 | 0.77 | TSHR (0.46) | ALOX15SMN1; SMN2TSHRTDP1TRPV1 | |
| SCHEMBL15987193 | 0.77 | SLC22A6 (0.42) | SMN1; SMN2LMNATDP1SLC22A6MAPT | |
| SCHEMBL7539461 | 0.77 | TSHR (0.46) | ALOX15SMN1; SMN2LMNATSHRTDP1 | |
| SCHEMBL886928 | 0.77 | SLC22A6 (0.42) | SMN1; SMN2LMNATDP1SLC22A6MAPT | |
| SCHEMBL9789654 | 0.76 | TSHR (0.41) | ALOX15SMN1; SMN2TSHRSLC22A6MAPT | |
| SCHEMBL16330194 | 0.76 | ALOX15 (0.42) | ALOX15SMN1; SMN2LMNATSHRTDP1 | |
| SCHEMBL9676795 | 0.75 | CACNA2D1 (0.43) | ALOX15SMN1; SMN2LMNATSHRTDP1 | |
| SCHEMBL4683182 | 0.75 | ALOX15 (0.57) | ALOX15SMN1; SMN2LMNATSHRTDP1 | |
| SCHEMBL10309227 | 0.75 | ALOX15 (0.57) | ALOX15SMN1; SMN2LMNATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858970-B1 | BLOCKY HYDROXYETHYLCELLULOSE, DERIVATIVES THEREOF, PROCESS OF MAKING, AND USES THEREOF | HERCULES INC (US) | 2008-08-20 | — | — | EP | disclosed |