SCHEMBL886928

SCHEMBL886928

COC(CC(=O)O)C(C)O

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.39
MAPT P10636 1/20 0.37
GABRR1 P24046 2/20 0.36
LMNA P02545 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
CACNA2D1 P54289 2/20 0.34
CACNB3 P54284 1/20 0.34
CACNA1C Q13936 1/20 0.34
PGR P06401 1/20 0.34
ADRA1A P35348 1/20 0.34
HTR2B P41595 1/20 0.34
CACNA2D2 Q9NY47 1/20 0.34
GPR84 Q9NQS5 4/20 0.33
TP53 P04637 1/20 0.33
PGD P52209 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15987193 1.00 SLC22A6 (0.42) SLC22A6SMN1; SMN2MAPTGABRR1LMNA
SCHEMBL498582 0.83 SLC22A6 (0.38) SLC22A6SMN1; SMN2MAPTGABRR1LMNA
SCHEMBL13424255 0.81 SLC22A6 (0.42) SLC22A6SMN1; SMN2MAPTGABRR1LMNA
SCHEMBL28772970 0.79 GABRP (0.38) SLC22A6SMN1; SMN2GABRR1LMNATDP1
SCHEMBL2985404 0.77 LMNA (0.40) SLC22A6SMN1; SMN2MAPTGABRR1LMNA
SCHEMBL22188543 0.77 TDP1 (0.38) TDP1
SCHEMBL4598341 0.77 ALOX15 (0.47) SLC22A6SMN1; SMN2MAPTGABRR1LMNA
SCHEMBL20543906 0.77 SLC22A6 (0.39) SLC22A6SMN1; SMN2MAPTGABRR1LMNA
SCHEMBL15987225 0.76 ATM (0.34) MAPTLMNA
SCHEMBL17484893 0.76 SLC22A6 (0.37) SLC22A6SMN1; SMN2MAPTGABRR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160129679-A1 METHOD FOR THE PRODUCTION OF A POLYCARBONATE LAMINATE BUNDESDRUCKEREI GMBH (DE) 2016-05-12 US claimed
EP-2205686-B1 METHOD FOR THE PRODUCTION OF A POLYCARBONATE LAMINATE BUNDESDRUCKEREI GMBH (DE) 2011-03-16 EP claimed
US-20100301595-A1 METHOD FOR THE PRODUCTION OF A POLYCARBONATE LAMINATE BUNDESDRUCKEREI GMBH (DE) 2010-12-02 US claimed
US-20220404703-A1 SEMICONDUCTOR DEVICE AND IMPRINT METHOD KIOXIA CORPORATION (JP) 2022-12-22 US disclosed
US-20210324372-A1 METHODS AND COMPOSITIONS FOR NUCLEIC ACID ISOLATION CEPHEID (US) 2021-10-21 US disclosed
EP-3837363-A1 METHODS AND COMPOSITIONS FOR NUCLEIC ACID ISOLATION Cepheid (US) 2021-06-23 EP disclosed
US-10723109-B2 Method for producing a polycarbonate layered composite COVESTRO DEUTSCHLAND AG (DE) 2020-07-28 US disclosed
WO-2020037260-A1 METHODS AND COMPOSITIONS FOR NUCLEIC ACID ISOLATION CEPHEID (US) 2020-02-20 WO disclosed
US-10551566-B2 Method of preparing an optical connector and optical devices comprising the optical connector prepared thereby DOW SILICONES CORPORATION (US) 2020-02-04 US disclosed
US-10435585-B2 Curable composition, method of preparing cured article, and cured article formed thereby DOW CORNING CORPORATION (US) 2019-10-08 US disclosed
US-10377116-B2 Method for the production of a polycarbonate laminate BUNDESDRUCKEREI GMBH (DE) 2019-08-13 US disclosed
US-20090124969-A1 Protective Coatings for Medical Devices BOSTON SCIENTIFIC SCIMED, INC. (US) 2009-05-14 US disclosed
US-7479128-B1 Protective coatings for medical devices BOSTON SCIENTIFIC SCIMED, INC. (US) 2009-01-20 US disclosed
US-20090012256-A1 curing through hydrosilylation; comprising a cured polysiloxane prepolymer containing two or more Si-H groups per molecule obtained by hydrosilylation reaction, and a cyclic siloxane compound with carbon-carbon double bonds; electronics; heat resistance, noncracking, alkali and solvent resistance, optics ADEKA CORPORATION (JP) 2009-01-08 US disclosed
US-20080058441-A1 Active Energy Ray-Curable, Organopolysiloxane Resin Composition, Light-Transmitting Component, And Method For Manufacturing The Light-Transmitting Component DOW TORAY CO., LTD. (JP) 2008-03-06 US disclosed
EP-1852469-A1 SILICON-CONTAINING CURABLE COMPOSITION AND ITS CURED PRODUCT Adeka Corporation (JP) 2007-11-07 EP disclosed
EP-1692209-A1 ACTIVE ENERGY RAY-CURABLE ORGANOPOLYSILOXANE RESIN COMPOSITION, LIGHT-TRANSMITTING COMPONENT, AND METHOD FOR MANUFACTURING THE LIGHT-TRANSMITTING COMPONENT Dow Corning Toray Co., Ltd. (JP) 2006-08-23 EP disclosed
WO-2005056640-A1 ACTIVE ENERGY RAY-CURABLE ORGANOPOLYSILOXANE RESIN COMPOSITION, LIGHT-TRANSMITTING COMPONENT, AND METHOD FOR MANUFACTURING THE LIGHT-TRANSMITTING COMPONENT DOW CORNING TORAY CO., LTD. (JP) 2005-06-23 WO disclosed
EP-1244479-B1 PROTECTIVE COATINGS FOR MEDICAL DEVICES BOSTON SCIENT LTD (BB) 2005-05-11 EP disclosed
US-5904504-A Die attach method and integrated circuit device FAIRCHILD SEMICONDUCTOR CORP. (US) 1999-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10435585-B2 Curable composition, method of preparing cured article, and cured article formed thereby SETDB1, SETD2, SETD1A SLC22A6 2171/4885SMN1; SMN2 368/4885MAPT 1258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.