SCHEMBL4598467

SCHEMBL4598467

Cc1oc(O)cc1Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.52
BCL2L1 Q07817 1/20 0.52
CNR2 P34972 1/20 0.47
GPR55 Q9Y2T6 1/20 0.47
ALOX5 P09917 2/20 0.46
MEN1 O00255 1/20 0.43
CYP3A4 P08684 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
KMT2A Q03164 1/20 0.43
HIF1A Q16665 1/20 0.43
HSD17B10 Q99714 1/20 0.43
HSD17B3 P37058 1/20 0.42
IDH1 O75874 1/20 0.40
NQO1 P15559 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9862150 0.79 BCL2 (0.44) BCL2BCL2L1CNR2GPR55ALOX5
SCHEMBL10828292 0.71 GPR55 (0.41) BCL2BCL2L1CNR2GPR55MEN1
SCHEMBL670158 0.71 BCL2 (0.57) BCL2BCL2L1ALOX5HIF1A
SCHEMBL8098213 0.71 CALM1 (0.55) BCL2BCL2L1CNR2GPR55ALOX5
SCHEMBL4599456 0.70 MAPK1 (0.48) BCL2BCL2L1CNR2GPR55ALOX5
Benzene SCHEMBL27915564 0.69 BCL2 (0.55) BCL2BCL2L1CNR2GPR55ALOX5
SCHEMBL5648473 0.69 BCL2 (0.55) BCL2BCL2L1CNR2GPR55ALOX5
SCHEMBL6687761 0.69 BCL2 (0.55) BCL2BCL2L1CNR2GPR55ALOX5
SCHEMBL31154610 0.69 BCL2 (0.61) BCL2BCL2L1ALOX5MEN1CYP3A4
SCHEMBL1904809 0.69 AMY1A (0.58) BCL2BCL2L1ALOX5HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1404661-B1 PROCESS FOR THE PRODUCTION OF 5-BENZYL-3-FURFURYL ALCOHOL ENDURA SPA (IT) 2008-04-09 EP disclosed
CN-1247560-C Process for the production of 5-benzyl-3-furfuryl alcohol ENDURA SPA (IT) 2006-03-29 CN disclosed
US-7019154-B2 Process for the production of 5-benzyl-3-furfuryl alcohol ENDURA S.P.A. (IT) 2006-03-28 US disclosed
US-20040127728-A1 Process for the production of 5-benzyl-3-furfuryl alcohol ENDURA S.P.A. (IT) 2004-07-01 US disclosed
CN-1507439-A Process for the production of 5-benzyl-3-furfuryl alcohol 2004-06-23 CN disclosed
EP-1404661-A1 PROCESS FOR THE PRODUCTION OF 5-BENZYL-3-FURFURYL ALCOHOL ENDURA S.p.A. (IT) 2004-04-07 EP disclosed
WO-2002090341-A1 PROCESS FOR THE PRODUCTION OF 5-BENZYL-3-FURFURYL ALCOHOL ENDURA S.P.A. (IT) 2002-11-14 WO disclosed