Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 7/20 | 0.44 |
| ▸ | CTSK | P43235 | 6/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14003045 | 1.00 | ITGB3 (0.47) | ITGB3ITGA2BCTSSCTSKCTSB | |
| SCHEMBL3867713 | 0.88 | ITGB3 (0.60) | ITGB3ITGA2BCTSSCTSKCTSB | |
| SCHEMBL3867720 | 0.88 | ITGB3 (0.60) | ITGB3ITGA2BCTSSCTSKCTSB | |
| SCHEMBL3868288 | 0.87 | KLK5 (0.50) | ITGB3ITGA2BCTSSCTSKCTSB | |
| SCHEMBL3868286 | 0.87 | KLK5 (0.50) | ITGB3ITGA2BCTSSCTSKCTSB | |
| SCHEMBL4826858 | 0.86 | ITGB3 (0.50) | ITGB3ITGA2BCTSSCTSKCTSB | |
| SCHEMBL14003050 | 0.86 | ITGB3 (0.50) | ITGB3ITGA2BCTSSCTSKCTSB | |
| SCHEMBL14021662 | 0.85 | ITGB3 (0.49) | ITGB3ITGA2BCTSSCTSKCTSB | |
| SCHEMBL4597076 | 0.85 | ITGB3 (0.49) | ITGB3ITGA2BCTSSCTSKCTSB | |
| SCHEMBL5151169 | 0.84 | CTSS (0.46) | ITGB3ITGA2BCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456292-B2 | Hydroxamic acid-containing amino acid derivatives | BEXEL PHARMACEUTICALS, INC. (US) | 2008-11-25 | — | — | US | disclosed |
| US-20080200521-A1 | Novel hydroxamic acid containing amino acid derivatives | BEXEL PHARMACEUTICALS. INC. | 2008-08-21 | — | — | US | disclosed |
| EP-1906731-A2 | NOVEL HYDROXAMIC ACID-CONTAINING AMINO ACID DERIVATIVES | Bexel Pharmaceuticals Inc (US) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007005603-A2 | NOVEL HYDROXAMIC ACID-CONTAINING AMINO ACID DERIVATIVES | BEXEL PHARMACEUTICALS, INC. (US) | 2007-01-11 | — | — | WO | disclosed |
| US-20070004776-A1 | Novel hydroxamic acid-containing amino acid derivatives | BEXEL PHARMACEUTICALS, INC. | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200521-A1 | Novel hydroxamic acid containing amino acid derivatives | HGFAC, HCAR2, BCAT1 | ITGB3 3012/4885ITGA2B 1533/4885CTSS 1501/4885 |
| US-20070004776-A1 | Novel hydroxamic acid-containing amino acid derivatives | HGFAC, HCAR2, BCAT1 | ITGB3 2787/4885ITGA2B 1615/4885CTSS 1585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.