Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.75 |
| ▸ | NPC1 | O15118 | 4/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.63 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.63 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666205 | 0.87 | RAB9A (0.74) | LTA4HNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3505916 | 0.86 | LTA4H (0.78) | LTA4HNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21067416 | 0.86 | LTA4H (1.00) | LTA4HNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4667938 | 0.86 | LTA4H (0.64) | LTA4HNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21295527 | 0.85 | MEN1 (0.77) | LTA4HNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14280159 | 0.84 | LTA4H (0.71) | LTA4HNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11390615 | 0.84 | NPC1 (0.64) | LTA4HNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2750411 | 0.84 | SMN1; SMN2 (0.75) | LTA4HNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL626379 | 0.84 | PTPN1 (0.86) | LTA4HNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3424405 | 0.84 | MEN1 (0.74) | LTA4HNPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008080223-A1 | COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE | MIGENIX INC. (CA) | 2008-07-10 | — | — | WO | disclosed |
| EP-1910279-A2 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007002639-A2 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2007-01-04 | — | — | WO | disclosed |
| WO-2007002639-A2 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2007-01-04 | — | — | WO | disclosed |