Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.64 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.62 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4598560 | 0.86 | LTA4H (0.75) | LTA4HPARP10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9188352 | 0.82 | LTA4H (0.61) | LTA4HNPC1RAB9ASMN1; SMN2NR4A1 | |
| SCHEMBL27764698 | 0.81 | MEN1 (0.67) | LTA4HNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3505916 | 0.79 | LTA4H (0.78) | LTA4HNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4666205 | 0.79 | RAB9A (0.74) | LTA4HNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21067416 | 0.78 | LTA4H (1.00) | LTA4HNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21295527 | 0.78 | MEN1 (0.77) | LTA4HNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| Pyridine SCHEMBL8616278 | 0.77 | MEN1 (0.57) | LTA4HNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29197117 | 0.77 | LTA4H (0.57) | LTA4HNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8402761 | 0.77 | LTA4H (0.56) | LTA4HNPC1RAB9ASMN1; SMN2NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654254-A4 | ANTIFUNGAL AZOLE DERIVATIVES HAVING A FLUOROVINYL MOIETY AND PROCESS FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2008-12-31 | — | — | EP | disclosed |
| US-20080027117-A1 | Antifungal Azole Derivatives Having a Fluorovinyl Moiety and Process for the Preparation Thereof | KOREA RESERACH INSTIITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-01-31 | — | — | US | disclosed |
| EP-1654254-A1 | ANTIFUNGAL AZOLE DERIVATIVES HAVING A FLUOROVINYL MOIETY AND PROCESS FOR THE PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005014583-A1 | ANTIFUNGAL AZOLE DERIVATIVES HAVING A FLUOROVINYL MOIETY AND PROCESS FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027117-A1 | Antifungal Azole Derivatives Having a Fluorovinyl Moiety and Process for the Preparation Thereof | ERG28, CYP51A1, CYP4F8 | LTA4H 4371/4885PARP10 3811/4885SIRT2 1721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.