Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20788954 | 1.00 | ANPEP (0.48) | ANPEPENPEPFOLH1TAAR1FFAR1 | |
| SCHEMBL30810322 | 0.82 | GRIA2 (0.55) | ANPEPENPEPFOLH1TAAR1EPHX1 | |
| SCHEMBL28828020 | 0.82 | ANPEP (0.49) | ANPEPENPEPFOLH1EPHX1CPA1 | |
| SCHEMBL28064623 | 0.82 | ANPEP (0.49) | ANPEPENPEPFOLH1EPHX1CPA1 | |
| SCHEMBL289224 | 0.82 | ANPEP (0.49) | ANPEPENPEPFOLH1THRATHRB | |
| SCHEMBL22607933 | 0.82 | FOLH1 (0.45) | FOLH1FFAR1FFAR4HCAR2ESR1 | |
| SCHEMBL22607932 | 0.82 | FOLH1 (0.45) | FOLH1FFAR1FFAR4HCAR2ESR1 | |
| SCHEMBL22734422 | 0.82 | GRIA2 (0.55) | ANPEPENPEPFOLH1TAAR1EPHX1 | |
| SCHEMBL28064622 | 0.82 | ANPEP (0.49) | ANPEPENPEPFOLH1EPHX1CPA1 | |
| SCHEMBL27999580 | 0.82 | ANPEP (0.49) | ANPEPENPEPFOLH1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4092038-A1 | OPIOID AGONIST PEPTIDES AND USES THEREOF | Protagonist Therapeutics, Inc. (US) | 2022-11-23 | — | — | EP | disclosed |
| US-20190076400-A1 | OPIOID AGONIST PEPTIDES AND USES THEREOF | PROTAGONIST THERAPEUTICS, INC. | 2019-03-14 | — | — | US | disclosed |
| US-20080306040-A1 | Antibacterial amide macrocycles VII | AICURIS GMBH & CO. KG (DE) | 2008-12-11 | — | — | US | disclosed |
| EP-1907413-A2 | ANTIBACTERIAL AMIDE MACROCYCLES VII | AiCuris GmbH & Co. KG (DE) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007006548-A2 | ANTIBACTERIAL AMIDE MACROCYCLES VII | AICURIS GMBH & CO. KG (DE) | 2007-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190076400-A1 | OPIOID AGONIST PEPTIDES AND USES THEREOF | OPRL1, OPRM1, OPRK1 | ANPEP 105/4885ENPEP 198/4885FOLH1 349/4885 |
| US-20080306040-A1 | Antibacterial amide macrocycles VII | AADAC, AAAS, NOD2 | ANPEP 196/4885ENPEP 90/4885FOLH1 2530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.