Stearic Acid

Stearic Acid

SCHEMBL4599006

CCCCCCCCCCCCCCCCCC(=O)[O-].c1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.49
CES1 P23141 2/20 0.49
EPHX2 P34913 1/20 0.49
HDAC3 O15379 1/20 0.49
HDAC4 P56524 1/20 0.49
HDAC1 Q13547 1/20 0.49
HDAC7 Q8WUI4 1/20 0.49
HDAC2 Q92769 1/20 0.49
HDAC10 Q969S8 1/20 0.49
HDAC11 Q96DB2 1/20 0.49
HDAC8 Q9BY41 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
HDAC9 Q9UKV0 1/20 0.49
HDAC5 Q9UQL6 1/20 0.49
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
PPARG P37231 2/20 0.47
FABP3 P05413 4/20 0.45
CETP P11597 3/20 0.44
PPARA Q07869 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Stearic Acid SCHEMBL8598208 0.89 EPHX2 (0.47) CES2CES1EPHX2HDAC3HDAC4
Heptanoate SCHEMBL28096384 0.87 MAPT (0.49) EPHX2HDAC11MEN1KMT2APPARG
Stearic Acid SCHEMBL8596126 0.87 CES2 (0.50) CES2CES1EPHX2HDAC3HDAC4
Stearic Acid SCHEMBL11514728 0.86 CES2 (0.53) CES2CES1EPHX2PPARGFABP3
Dodecanoate SCHEMBL30363216 0.81 HDAC3 (0.54) CES2CES1EPHX2HDAC3HDAC4
Acetic Acid SCHEMBL3842343 0.81 SNCA (0.55) CES2CES1HDAC3HDAC4HDAC1
Decanoic Acid SCHEMBL31119049 0.79 SLC7A5 (0.59) CES2CES1EPHX2HDAC3HDAC4
Decanoic Acid SCHEMBL29031142 0.79 SLC7A5 (0.59) CES2CES1EPHX2HDAC3HDAC4
Stearic Acid SCHEMBL11045268 0.79 HDAC3 (0.51) CES2CES1EPHX2HDAC3HDAC4
Dodecanoate SCHEMBL673994 0.79 HDAC3 (0.51) CES2CES1EPHX2HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5658671-A ARTICLE COATED WITH COMPOSITION COMPRISING FLUOROELASTOMER, QUATERNARY AMMONIUM OR PHOSPHONIUM ACCELERATOR, POLYOL, ACID ACCEPTOR, OIL-SOLUBLE CHELATING AGENT, ORGANIC SOLVENT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-08-19 US claimed
US-5451625-A FOR USE IN THE PREPARATION OF AUTOMOTIVE GASKETS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-09-19 US claimed
EP-0574319-A1 Fluoroelastomer coating composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-12-15 EP claimed
EP-1453896-B1 PROCESS FOR MODIFYING A POLYMERIC SURFACE 3M INNOVATIVE PROPERTIES CO (US) 2008-04-09 EP disclosed
EP-1461376-B1 IMPROVED PROCESS FOR MODIFYING A POLYMERIC SURFACE 3M INNOVATIVE PROPERTIES CO (US) 2006-12-20 EP disclosed
EP-1578849-A1 METHOD FOR MODIFYING THE SURFACE OF A POLYMERIC SUBSTRATE 3M Innovative Properties Company (US) 2005-09-28 EP disclosed
US-6844030-B2 Process for modifying a polymeric surface 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-01-18 US disclosed
EP-1461376-A1 IMPROVED PROCESS FOR MODIFYING A POLYMERIC SURFACE 3M Innovative Properties Company (US) 2004-09-29 EP disclosed
EP-1453896-A1 PROCESS FOR MODIFYING A POLYMERIC SURFACE 3M Innovative Properties Company (US) 2004-09-08 EP disclosed
WO-2004060983-A1 METHOD FOR MODIFYING THE SURFACE OF A POLYMERIC SUBSTRATE 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-07-22 WO disclosed
US-20040126708-A1 Digitally applying a photoreactive material comprising photochemical electron donor exposing to actinic radiation 3M INNOVATIVE PROPERTIES COMPANY 2004-07-01 US disclosed
WO-2003051966-A1 IMPROVED PROCESS FOR MODIFYING A POLYMERIC SURFACE 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-06-26 WO disclosed
WO-2003051965-A1 PROCESS FOR MODIFYING A POLYMERIC SURFACE 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-06-26 WO disclosed
EP-0574319-B1 Fluoroelastomer coating composition DYNEON LLC (US) 1998-01-21 EP disclosed
US-5658671-A ARTICLE COATED WITH COMPOSITION COMPRISING FLUOROELASTOMER, QUATERNARY AMMONIUM OR PHOSPHONIUM ACCELERATOR, POLYOL, ACID ACCEPTOR, OIL-SOLUBLE CHELATING AGENT, ORGANIC SOLVENT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-08-19 US disclosed
EP-0670868-B1 FLUORORUBBER COATING COMPOSITION MINNESOTA MINING & MFG (US) 1997-01-22 EP disclosed
US-5451625-A FOR USE IN THE PREPARATION OF AUTOMOTIVE GASKETS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-09-19 US disclosed
EP-0670868-A1 FLUORORUBBER COATING COMPOSITION. MINNESOTA MINING & MFG (US) 1995-09-13 EP disclosed
WO-1994012580-A1 FLUORORUBBER COATING COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-06-09 WO disclosed
EP-0574319-A1 Fluoroelastomer coating composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-12-15 EP disclosed