Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.53 |
| ▸ | CES1 | P23141 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | FABP3 | P05413 | 7/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL679440 | 0.88 | CYP2C19 (0.50) | CES2CES1PPARGCA1 | |
| Stearic Acid SCHEMBL4599006 | 0.86 | CES2 (0.49) | CES2CES1PPARGFABP3PPARA | |
| Propionic Acid SCHEMBL1399930 | 0.83 | CYP1A2 (0.47) | CES2CES1 | |
| Bicarbonate SCHEMBL1144353 | 0.82 | CYP1A2 (0.50) | CES2CES1 | |
| Bicarbonate SCHEMBL11663344 | 0.82 | CYP1A2 (0.50) | CES2CES1 | |
| Octanoic Acid SCHEMBL2807929 | 0.81 | CES2 (0.57) | CES2CES1PPARGFABP3CA1 | |
| Dodecanoate SCHEMBL10935524 | 0.81 | CES2 (0.57) | CES2CES1PPARGFABP3CA1 | |
| Decanoic Acid SCHEMBL10862164 | 0.81 | CES2 (0.57) | CES2CES1PPARGFABP3CA1 | |
| Stearic Acid SCHEMBL11768053 | 0.81 | CES2 (0.57) | CES2CES1PPARGFABP3PPARA | |
| Oxalic Acid SCHEMBL10577823 | 0.81 | CYP1A2 (0.48) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145473-A | Antistatic filament having a polymeric sheath and a conductive polymeric core | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-03-20 | — | — | US | disclosed |