SCHEMBL459925

SCHEMBL459925

CCO/C(C)=N/C(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
ALDH1A1 P00352 3/20 0.47
NPC1 O15118 2/20 0.47
MAPT P10636 2/20 0.47
SMN1; SMN2 Q16637 4/20 0.45
KDM4E B2RXH2 1/20 0.45
NFKB1 P19838 1/20 0.45
NFKB2 Q00653 1/20 0.45
RELA Q04206 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
LMNA P02545 1/20 0.44
TSHR P16473 1/20 0.44
GAA P10253 2/20 0.43
RAB9A P51151 1/20 0.43
CYP19A1 P11511 2/20 0.41
PIN1 Q13526 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9604202 1.00 MEN1 (0.47) MEN1KMT2AALDH1A1NPC1MAPT
SCHEMBL515715 1.00 MEN1 (0.47) MEN1KMT2AALDH1A1NPC1MAPT
SCHEMBL5205967 0.86 ALDH1A1 (0.45) KMT2AALDH1A1NPC1MAPTSMN1; SMN2
SCHEMBL5206539 0.86 ALDH1A1 (0.45) KMT2AALDH1A1NPC1MAPTSMN1; SMN2
SCHEMBL5201729 0.83 SMN1; SMN2 (0.50) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL5201537 0.83 MAPT (0.48) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL5201790 0.83 RXFP1 (0.47) MEN1KMT2AALDH1A1NPC1MAPT
SCHEMBL5205877 0.83 RXFP1 (0.47) MEN1KMT2AALDH1A1NPC1MAPT
SCHEMBL5204972 0.83 SMN1; SMN2 (0.50) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL5201536 0.83 MAPT (0.48) MEN1KMT2AALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577456-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2026-03-17 US disclosed
US-20240026217-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-01-25 US disclosed
US-20240026217-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-01-25 US disclosed
US-20240026217-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-01-25 US disclosed
US-11773321-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2023-10-03 US disclosed
US-11773321-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2023-10-03 US disclosed
US-11773321-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2023-10-03 US disclosed
US-20210277305-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-09-09 US disclosed
US-20210277305-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-09-09 US disclosed
US-11008510-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2021-05-18 US disclosed
EP-1458706-B1 DIARYL 1,2,4-TRIAZOLE DERIVATIVES AS A HIGHLY SELECTIVE CYCLOOXYGENASE-2 INHIBITOR CJ CORP (KR) 2007-07-11 EP disclosed
US-7169929-B2 Diaryl 1,2,4-triazole derivatives as a highly selective cyclooxygenase-2 inhibitor CJ CORP. (KR) 2007-01-30 US disclosed
US-7135572-B2 Diaryl 1,2,4-triazole derivatives as a highly selective cyclooxygenase-2 inhibitor CJ CORP (KR) 2006-11-14 US disclosed
US-20060009495-A1 Diary 1,2,4-triazole derivatives as a highly selective cyclooxygenase-2 inhibitor CJ CORP. (KR) 2006-01-12 US disclosed
EP-1611128-A2 POSITIVE ALLOSTERIC MODULATORS OF THE NICOTINIC ACETYLCHOLINE RECEPTOR Pharmacia & Upjohn Company LLC (US) 2006-01-04 EP disclosed
EP-1458706-A4 DIARYL 1,2,4-TRIAZOLE DERIVATIVES AS A HIGHLY SELECTIVE CYCLOOXYGENASE-2 INHIBITOR CJ CORP (KR) 2005-06-08 EP disclosed
US-20050075373-A1 Diaryl 1,2,4-triazole derivatives as a highly selective cyclooxygenase-2 inhibitor CJ CORP. (KR) 2005-04-07 US disclosed
WO-2004085433-A2 POSITIVE ALLOSTERIC MODULATORS OF THE NICOTINIC ACETYLCHOLINE RECEPTOR PHARMACIA & UPJOHN COMPANY LLC (US) 2004-10-07 WO disclosed
EP-1458706-A1 DIARYL 1,2,4-TRIAZOLE DERIVATIVES AS A HIGHLY SELECTIVE CYCLOOXYGENASE-2 INHIBITOR CJ Corp. (KR) 2004-09-22 EP disclosed
WO-2003055875-A1 DIARYL 1,2,4-TRIAZOLE DERIVATIVES AS A HIGHLY SELECTIVE CYCLOOXYGENASE-2 INHIBITOR CJ CORP. (KR) 2003-07-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060009495-A1 Diary 1,2,4-triazole derivatives as a highly selective cyclooxygenase-2 inhibitor PTGS1, PTGS2, PTGES2 MEN1 4228/4885KMT2A 850/4885ALDH1A1 110/4885
US-20050075373-A1 Diaryl 1,2,4-triazole derivatives as a highly selective cyclooxygenase-2 inhibitor PTGS1, PTGS2, PTGES2 MEN1 4392/4885KMT2A 1195/4885ALDH1A1 120/4885
US-12577456-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SUN2, LEF1, CTNND1 MEN1 893/4885KMT2A 2087/4885ALDH1A1 984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.