Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2992730 | 0.93 | TSHR (0.45) | TSHRALDH1A1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL3972957 | 0.89 | ALDH1A1 (0.51) | TSHRALDH1A1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL5416441 | 0.86 | TSHR (0.54) | TSHRALDH1A1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL2937590 | 0.86 | ALDH1A1 (0.50) | TSHRALDH1A1CYP3A4TDP1KDM4E | |
| Di(Hydroxyethyl)Ether SCHEMBL839491 | 0.85 | ALDH1A1 (0.41) | TSHRALDH1A1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL633205 | 0.85 | TSHR (0.68) | TSHRALDH1A1CYP3A4TDP1L3MBTL1 | |
| Ethane SCHEMBL16393958 | 0.84 | ALDH1A1 (0.48) | TSHRALDH1A1CYP3A4TDP1KDM4E | |
| SCHEMBL31059332 | 0.82 | TSHR (0.46) | TSHRALDH1A1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL16990763 | 0.82 | ALDH1A1 (0.70) | TSHRALDH1A1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL11339716 | 0.82 | LMNA (0.56) | TSHRALDH1A1CYP3A4TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452489-B1 | MATERIAL FOR IMPARTING THIXOTROPY AND PASTY RESIN COMPOSITION | SHIRAISHI KOGYO KAISHA LTD (JP) | 2008-04-09 | — | — | EP | disclosed |
| US-7186763-B2 | Material for imparting thixotropy and pasty resin composition | SHIRAISHI KOGYO KAISHA, LTD. (JP) | 2007-03-06 | — | — | US | disclosed |
| US-20050004266-A1 | Calcium carbonate surface treated with combination of unsaturated and saturated fatty acids; low cost, storage stability | SHIRAISHI KOGYO KAISHA, LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-1452489-A1 | MATERIAL FOR IMPARTING THIXOTROPY AND PASTY RESIN COMPOSITION | Shiraishi Kogyo Kaisha, Ltd. (JP) | 2004-09-01 | — | — | EP | disclosed |