SCHEMBL4599792

SCHEMBL4599792

Cc1ccc(S(=O)(=O)Oc2cccc(CC(C)C)c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
LMNA P02545 1/20 0.46
HPGD P15428 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
MAOB P27338 1/20 0.45
DRD2 P14416 1/20 0.44
DRD1 P21728 1/20 0.44
DRD4 P21917 1/20 0.44
DRD5 P21918 1/20 0.44
DRD3 P35462 1/20 0.44
GPR17 Q13304 1/20 0.43
F2 P00734 1/20 0.42
GAA P10253 2/20 0.42
MAPT P10636 1/20 0.42
G6PD P11413 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
KEAP1 Q14145 1/20 0.42
NFE2L2 Q16236 1/20 0.42
CYP19A1 P11511 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4599286 0.89 ALDH1A1 (0.48) ALDH1A1LMNAMAOBF2GAA
SCHEMBL1824240 0.87 ALDH1A1 (0.44) ALDH1A1LMNAHPGDMEN1KMT2A
SCHEMBL1827598 0.83 SIGMAR1 (0.49) ALDH1A1LMNAHPGDGPR17GAA
SCHEMBL1828347 0.83 GAA (0.49) ALDH1A1MEN1KMT2AGPR17GAA
SCHEMBL14878587 0.82 ENPP1 (0.49) ALDH1A1LMNAMEN1KMT2AMAPT
SCHEMBL1826211 0.82 ALDH1A1 (0.42) ALDH1A1LMNAHPGDMEN1KMT2A
SCHEMBL874701 0.82 ALDH1A1 (0.40) ALDH1A1LMNAHPGDMEN1KMT2A
SCHEMBL6939231 0.81 MEN1 (0.49) ALDH1A1LMNAHPGDMEN1KMT2A
SCHEMBL1824966 0.79 GAA (0.51) ALDH1A1LMNAHPGDMEN1KMT2A
SCHEMBL4599115 0.79 TAAR1 (0.47) ALDH1A1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1910320-A2 INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF Mitsubishi Tanabe Pharma Corporation (JP) 2008-04-16 EP claimed
WO-2007011065-A2 INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-01-25 WO claimed
EP-1910320-A2 INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF Mitsubishi Tanabe Pharma Corporation (JP) 2008-04-16 EP disclosed
WO-2007011065-A2 INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-01-25 WO disclosed