Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1826211 | 0.85 | ALDH1A1 (0.42) | ALDH1A1DRD2DRD1DRD4DRD5 | |
| SCHEMBL1824240 | 0.85 | ALDH1A1 (0.44) | ALDH1A1DRD2DRD1DRD4DRD5 | |
| SCHEMBL4599792 | 0.82 | ALDH1A1 (0.47) | ALDH1A1DRD2DRD1DRD4DRD5 | |
| SCHEMBL1824312 | 0.75 | GPR17 (0.43) | ALDH1A1DRD2DRD1DRD4DRD5 | |
| SCHEMBL1823435 | 0.75 | L3MBTL1 (0.42) | ALDH1A1DRD2DRD1DRD4DRD5 | |
| SCHEMBL1825788 | 0.74 | ALDH1A1 (0.47) | ALDH1A1DRD2DRD1DRD4DRD5 | |
| SCHEMBL1827598 | 0.74 | SIGMAR1 (0.49) | ALDH1A1HPGDLMNAGPR17L3MBTL1 | |
| SCHEMBL1828347 | 0.74 | GAA (0.49) | ALDH1A1MEN1KMT2AGPR17MAPT | |
| SCHEMBL3573281 | 0.73 | ACHE (0.50) | ALDH1A1DRD2DRD1DRD4DRD5 | |
| SCHEMBL874700 | 0.73 | SLC22A1 (0.51) | ALDH1A1DRD2DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619174-A1 | PROCESS FOR PREPARING L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVE | Ind-Swift Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038974-A1 | PROCESS FOR PREPARING L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVE | IND-SWIFT LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |