Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TNF | P01375 | 1/20 | 0.53 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600567 | 0.89 | KMT2A (0.82) | KMT2APPARGRXFP1NCOR2 | |
| SCHEMBL4599900 | 0.88 | KMT2A (0.70) | KMT2APPARGRXFP1NCOR2NPC1 | |
| SCHEMBL2785360 | 0.82 | TDP1 (0.54) | KMT2ARAB9A | |
| SCHEMBL5215974 | 0.81 | ALDH1A1 (0.61) | KMT2A | |
| SCHEMBL10969124 | 0.81 | P2RY1 (0.60) | KMT2ATRPV1NPC1 | |
| SCHEMBL135002 | 0.80 | P2RY1 (0.72) | KMT2A | |
| SCHEMBL29549324 | 0.80 | P2RY1 (0.72) | KMT2A | |
| SCHEMBL4939060 | 0.79 | KMT2A (0.82) | KMT2A | |
| SCHEMBL3960247 | 0.79 | KDR (0.78) | KMT2ANPC1RAB9A | |
| SCHEMBL11730950 | 0.79 | NPC1 (0.77) | TRPV1NPC1RAB9AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910295-A1 | SUBSTITUTED PYRIDOCARBOXAMIDES AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR 1 (PAI-1) | Bayer HealthCare AG (DE) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007028456-A1 | SUBSTITUTED PYRIDOCARBOXAMIDES AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR 1 (PAI-1) | BAYER HEALTHCARE AG (DE) | 2007-03-15 | — | — | WO | disclosed |