Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | KIF11 | P52732 | 9/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285131 | 0.88 | KIF11 (0.46) | TAAR1KIF11SMN1; SMN2KCNH2KCNN4 | |
| SCHEMBL11569782 | 0.85 | KIF11 (0.64) | TAAR1KIF11SMN1; SMN2KCNH2 | |
| SCHEMBL11567805 | 0.81 | TAAR1 (0.41) | TAAR1KIF11SMN1; SMN2KCNH2CYP3A4 | |
| SCHEMBL5147319 | 0.81 | TAAR1 (0.67) | TAAR1KIF11SMN1; SMN2KCNH2CYP3A4 | |
| SCHEMBL460018 | 0.80 | TAAR1 (0.65) | TAAR1KIF11SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL28268687 | 0.80 | TAAR1 (0.46) | TAAR1KIF11CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11431197 | 0.79 | TAAR1 (0.52) | TAAR1KIF11SMN1; SMN2KCNH2CYP3A4 | |
| SCHEMBL3963163 | 0.78 | TAAR1 (0.44) | TAAR1KIF11CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL3241793 | 0.78 | TAAR1 (0.62) | TAAR1KIF11SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL4166810 | 0.77 | TAAR1 (0.50) | TAAR1KIF11SMN1; SMN2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9190521-B2 | Positive photosensitive resin composition and uses thereof | CHI MEI CORPORATION (TW) | 2015-11-17 | — | — | US | disclosed |
| US-20130306970-A1 | POSITIVE PHOTOSENSITIVE RESIN COMPOSITION AND USES THEREOF | CHI MEI CORPORATION (TW) | 2013-11-21 | — | — | US | disclosed |
| US-20130164461-A1 | POSITIVE PHOTOSENSITIVE RESIN COMPOSITION AND USES THEREOF | CHI MEI CORPORATION (TW) | 2013-06-27 | — | — | US | disclosed |
| EP-1824824-A1 | INTERMEDIATES FOR THE PREPARATION OF LERCANIDIPINE | Motivan Ltd. (IL) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006059332-A1 | INTERMEDIATES FOR THE PREPARATION OF LERCANIDIPINE | MOTIVAN LTD. (IL) | 2006-06-08 | — | — | WO | disclosed |
| EP-1161421-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | Pharmacia & Upjohn Aktiebolag (SE) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000053583-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | BIOVITRUM AB (SE) | 2000-09-14 | — | — | WO | disclosed |
| EP-0262448-B1 | IMIDAZOLYLGUANIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | HEUMANN PHARMA GMBH & CO (DE) | 1991-12-18 | — | — | EP | disclosed |
| US-4912119-A | Cardiovascular disorders | HEUMANN PHARMA GMBH & CO. (DE) | 1990-03-27 | — | — | US | disclosed |
| EP-0262448-A1 | Imidazolylguanidine derivatives, process for their preparation and medicines containing them | HEUMANN PHARMA GMBH & CO (DE) | 1988-04-06 | — | — | EP | disclosed |