Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772497 | 0.93 | SMN1; SMN2 (0.49) | HPGDHSD17B10PTGDR2SMN1; SMN2MAPT | |
| SCHEMBL2723239 | 0.88 | ALDH1A1 (0.56) | HPGDHSD17B10ARPTGDR2SMN1; SMN2 | |
| SCHEMBL16997485 | 0.87 | HSD17B10 (0.49) | HPGDHSD17B10PTGDR2SMN1; SMN2MAPT | |
| SCHEMBL7371844 | 0.86 | PTGDR2 (0.56) | HPGDHSD17B10ARPTGDR2SMN1; SMN2 | |
| SCHEMBL20471949 | 0.85 | HSD17B10 (0.48) | HPGDHSD17B10PTGDR2SMN1; SMN2MAPT | |
| SCHEMBL17973700 | 0.84 | PTGDR2 (0.68) | HPGDHSD17B10ARPTGDR2SMN1; SMN2 | |
| SCHEMBL27039988 | 0.84 | ALDH1A1 (0.51) | HPGDHSD17B10PTGDR2SMN1; SMN2MAPT | |
| SCHEMBL20472002 | 0.84 | HSD17B10 (0.47) | HPGDHSD17B10PTGDR2SMN1; SMN2MAPT | |
| SCHEMBL5927172 | 0.83 | HPGD (0.52) | HPGDHSD17B10ARPTGDR2SMN1; SMN2 | |
| SCHEMBL11328546 | 0.83 | PLA2G2A (0.48) | HPGDHSD17B10SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240041837-A1 | TRIAZOLONE COMPOUNDS AND USES THEREOF | TEMPEST THERAPEUTICS, INC. | 2024-02-08 | — | — | US | disclosed |
| US-11666557-B2 | Triazolone compounds and uses thereof | TEMPEST THERAPEUTICS, INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-11666557-B2 | Triazolone compounds and uses thereof | TEMPEST THERAPEUTICS, INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-11666557-B2 | Triazolone compounds and uses thereof | TEMPEST THERAPEUTICS, INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-20200138790-A1 | TRIAZOLONE COMPOUNDS AND USES THEREOF | TEMPEST THERAPEUTICS, INC. | 2020-05-07 | — | — | US | disclosed |
| US-20200138790-A1 | TRIAZOLONE COMPOUNDS AND USES THEREOF | TEMPEST THERAPEUTICS, INC. | 2020-05-07 | — | — | US | disclosed |
| US-10568871-B2 | Triazolone compounds and uses thereof | TEMPEST THERAPEUTICS, INC. (US) | 2020-02-25 | — | — | US | disclosed |
| US-10568871-B2 | Triazolone compounds and uses thereof | TEMPEST THERAPEUTICS, INC. (US) | 2020-02-25 | — | — | US | disclosed |
| EP-2935228-B9 | TRIAZOLONE COMPOUNDS AND USES THEREOF | INCEPTION 2 INC (US) | 2017-12-06 | — | — | EP | disclosed |
| EP-2935228-B9 | TRIAZOLONE COMPOUNDS AND USES THEREOF | INCEPTION 2 INC (US) | 2017-12-06 | — | — | EP | disclosed |
| US-20150080412-A1 | TRIAZOLONE COMPOUNDS AND USES THEREOF | INCEPTION 2, INC. (US) | 2015-03-19 | — | — | US | disclosed |
| US-20150080412-A1 | TRIAZOLONE COMPOUNDS AND USES THEREOF | INCEPTION 2, INC. (US) | 2015-03-19 | — | — | US | disclosed |
| EP-2822931-A1 | TRIAZOLONE COMPOUNDS AND USES THEREOF | Inception 2, Inc. (US) | 2015-01-14 | — | — | EP | disclosed |
| WO-2014099503-A1 | TRIAZOLONE COMPOUNDS AND USES THEREOF | INCEPTION 2, INC. (US) | 2014-06-26 | — | — | WO | disclosed |
| WO-2014099503-A1 | TRIAZOLONE COMPOUNDS AND USES THEREOF | INCEPTION 2, INC. (US) | 2014-06-26 | — | — | WO | disclosed |
| WO-2013134562-A1 | TRIAZOLONE COMPOUNDS AND USES THEREOF | INCEPTION 2, INC. (US) | 2013-09-12 | — | — | WO | disclosed |
| WO-2013134562-A1 | TRIAZOLONE COMPOUNDS AND USES THEREOF | INCEPTION 2, INC. (US) | 2013-09-12 | — | — | WO | disclosed |
| EP-1912970-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-04-23 | — | — | EP | disclosed |
| US-20070060573-A1 | Acyltryptophanols | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
| WO-2007017289-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11666557-B2 | Triazolone compounds and uses thereof | PPARA, PPARG, PPARD | HPGD 2329/4885HSD17B10 497/4885AR 51/4885 |
| US-20240041837-A1 | TRIAZOLONE COMPOUNDS AND USES THEREOF | PPARA, PPARG, PPARD | HPGD 2329/4885HSD17B10 497/4885AR 51/4885 |
| US-10568871-B2 | Triazolone compounds and uses thereof | PPARA, PPARG, PPARD | HPGD 2329/4885HSD17B10 497/4885AR 51/4885 |
| US-20200138790-A1 | TRIAZOLONE COMPOUNDS AND USES THEREOF | PPARA, PPARG, PPARD | HPGD 2329/4885HSD17B10 497/4885AR 51/4885 |
| US-20150080412-A1 | TRIAZOLONE COMPOUNDS AND USES THEREOF | PPARA, PPARG, PPARD | HPGD 1996/4885HSD17B10 418/4885AR 37/4885 |
| US-20070060573-A1 | Acyltryptophanols | FSHR, NPY1R, NPY2R | HPGD 2557/4885HSD17B10 2116/4885AR 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.