Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAB2 | O43741 | 3/20 | 0.55 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.55 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.55 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.55 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.55 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.55 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.55 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | EIF4E | P06730 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28036196 | 0.88 | SMN1; SMN2 (0.60) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| Hydrochloric Acid SCHEMBL30823011 | 0.85 | PRKAB2 (0.50) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL17454033 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2RAB9APOLBMEN1KMT2A | |
| SCHEMBL29263230 | 0.84 | HPGD (0.58) | SMN1; SMN2RAB9APOLBMEN1KMT2A | |
| SCHEMBL14397805 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2RAB9APOLBMEN1KMT2A | |
| SCHEMBL16107035 | 0.82 | SMN1; SMN2 (0.53) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| Formaldehyde SCHEMBL29266746 | 0.82 | HPGD (0.55) | SMN1; SMN2RAB9APOLBMEN1KMT2A | |
| SCHEMBL19320907 | 0.81 | SMN1; SMN2 (0.51) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL22537008 | 0.80 | NPC1 (0.55) | GRM2SMN1; SMN2RAB9ATP53KDM4E | |
| SCHEMBL5149285 | 0.80 | HDAC4 (0.60) | SMN1; SMN2RAB9APOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912970-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007017289-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | WO | disclosed |