Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3620717 | 0.88 | KDM4E (0.44) | ALDH1A1KDM4EHPGDHSD17B10CNR1 | |
| SCHEMBL15362025 | 0.80 | CNR1 (0.39) | ALDH1A1KDM4EHPGDHSD17B10CNR1 | |
| SCHEMBL4600433 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10CCR2 | |
| SCHEMBL13802523 | 0.76 | CCR2 (0.62) | ALDH1A1KDM4EHPGDHSD17B10CCR2 | |
| SCHEMBL12466547 | 0.76 | ALDH1A1 (0.66) | ALDH1A1KDM4EHPGDHSD17B10CCR2 | |
| SCHEMBL12466305 | 0.74 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDHSD17B10CCR2 | |
| SCHEMBL7378692 | 0.73 | ALDH1A1 (0.65) | ALDH1A1KDM4EHPGDHSD17B10CCR2 | |
| SCHEMBL21647634 | 0.73 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10CCR2 | |
| SCHEMBL15362047 | 0.72 | KDM4E (0.48) | ALDH1A1KDM4EHPGDHSD17B10CCR2 | |
| SCHEMBL3114834 | 0.72 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910335-B1 | N-(HETEROARYL)-1-HETEROARYLALKYL-1H-INDOLE-2-CARBOXAMIDE DERIVATIVES, PREPARATION AND USE THEREOF | SANOFI SA (FR) | 2013-11-06 | — | — | EP | claimed |
| EP-1910335-A1 | N-(HETEROARYL)-1-HETEROARYLALKYL-1H-INDOLE-2-CARBOXAMIDE DERIVATIVES, PREPARATION AND USE THEREOF | Sanofi-Aventis (FR) | 2008-04-16 | — | — | EP | claimed |
| WO-2007010144-A1 | N-(HETEROARYL)-1-HETEROARYLALKYL-1H-INDOLE-2-CARBOXAMIDE DERIVATIVES, PREPARATION AND USE THEREOF | SANOFI-AVENTIS (FR) | 2007-01-25 | — | — | WO | claimed |