Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | IDH2 | P48735 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28475668 | 0.78 | MEN1 (0.41) | MEN1RAB9AKMT2ADHODHMAPT | |
| SCHEMBL28891807 | 0.78 | MEN1 (0.41) | MEN1RAB9AKMT2ADHODHMAPT | |
| SCHEMBL28424375 | 0.75 | MEN1 (0.41) | MEN1RAB9AKMT2ADHODHMAPT | |
| SCHEMBL4600429 | 0.73 | MEN1 (0.36) | ARMEN1RAB9AKMT2AMETAP2 | |
| SCHEMBL28462492 | 0.72 | MEN1 (0.44) | MEN1RAB9AKMT2AMAPTBACE1 | |
| SCHEMBL2599654 | 0.72 | MEN1 (0.44) | MEN1RAB9AKMT2AMAPTBACE1 | |
| SCHEMBL29044538 | 0.71 | BACE1 (0.39) | ARMEN1RAB9AKMT2ABACE1 | |
| SCHEMBL27784700 | 0.71 | SQOR (0.36) | METAP2FFAR4DHODH | |
| SCHEMBL16056335 | 0.71 | ALDH1A1 (0.39) | MEN1RAB9AKMT2AMAPT | |
| SCHEMBL6535943 | 0.70 | ALDH1A1 (0.45) | ARMEN1RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910292-A1 | PIPERIDINE DERIVATIVE AS TACHYKININ RECEPTOR ANTAGONIST | Takeda Pharmaceutical Company Limited (JP) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007015588-A1 | PIPERIDINE DERIVATIVE AS TACHYKININ RECEPTOR ANTAGONIST | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-08 | — | — | WO | disclosed |