Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11866234 | 0.85 | MAP4K1 (0.32) | MAP4K1 | |
| SCHEMBL460054 | 0.83 | TDP1 (0.38) | TDP1ALDH1A1MEN1POLBMAPT | |
| SCHEMBL20210937 | 0.76 | TDP1 (0.33) | TDP1ALDH1A1TSHRCA2 | |
| SCHEMBL4249599 | 0.76 | TDP1 (0.33) | TDP1ALDH1A1TSHRCA2 | |
| SCHEMBL10887280 | 0.75 | CYP3A4 (0.41) | TDP1ALDH1A1MEN1NPC1POLB | |
| SCHEMBL9032233 | 0.75 | MAP4K1 (0.33) | ALDH1A1MEN1KMT2AL3MBTL1MAP4K1 | |
| SCHEMBL28856679 | 0.74 | CA2 (0.36) | TDP1ALDH1A1MEN1POLBMAPT | |
| SCHEMBL28750839 | 0.74 | MEN1 (0.32) | TDP1ALDH1A1MEN1NPC1POLB | |
| SCHEMBL4640020 | 0.74 | TAAR1 (0.48) | ALDH1A1MEN1MAPTBLMKMT2A | |
| SCHEMBL5690489 | 0.74 | CYP3A4 (0.56) | TDP1ALDH1A1MEN1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014591-A1 | 2-ACYLAMINO OR 2-SULFONYLAMINO-1, 3-THIAZOLES AS COUPLERS FOR THE OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2005-02-17 | — | — | WO | disclosed |