Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.68 |
| ▸ | FFAR1 | O14842 | 10/20 | 0.64 |
| ▸ | MAOA | P21397 | 4/20 | 0.59 |
| ▸ | MAOB | P27338 | 4/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.58 |
| ▸ | THRA | P10827 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | PTPRB | P23467 | 1/20 | 0.51 |
| ▸ | CDC25A | P30304 | 1/20 | 0.51 |
| ▸ | CDC25B | P30305 | 1/20 | 0.51 |
| ▸ | PTEN | P60484 | 1/20 | 0.51 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL360723 | 0.93 | THRA (0.62) | CYP19A1FFAR1MAOAMAOBKEAP1 | |
| Hydrochloric Acid SCHEMBL6774044 | 0.91 | MAOA (0.63) | CYP19A1FFAR1MAOAMAOBKEAP1 | |
| SCHEMBL73828 | 0.86 | FFAR1 (0.65) | FFAR1MAOAMAOBKEAP1FFAR4 | |
| SCHEMBL27544320 | 0.84 | FFAR1 (0.63) | FFAR1MAOAMAOBKEAP1FFAR4 | |
| Hydrochloric Acid SCHEMBL3128046 | 0.84 | FFAR1 (0.63) | FFAR1MAOAMAOBKEAP1FFAR4 | |
| SCHEMBL1162158 | 0.83 | HDAC3 (0.63) | CYP19A1FFAR1MAOAMAOBKEAP1 | |
| SCHEMBL12646502 | 0.82 | FFAR1 (0.69) | CYP19A1FFAR1MAOAKEAP1THRA | |
| SCHEMBL27611502 | 0.81 | MAPT (0.62) | CYP19A1FFAR1MAOAMAOBTHRA | |
| Hydrochloric Acid SCHEMBL8882353 | 0.81 | HDAC3 (0.61) | CYP19A1FFAR1MAOAMAOBTHRA | |
| SCHEMBL8339608 | 0.80 | FFAR1 (0.71) | FFAR1MAOAMAOBKEAP1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910279-A2 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007002639-A2 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2007-01-04 | — | — | WO | disclosed |