Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884767 | 0.82 | LTA4H (0.58) | L3MBTL1LMNAALOX5NPY5RRAB9A | |
| SCHEMBL7907782 | 0.81 | NR1H4 (0.59) | L3MBTL1LMNAALDH1A1NR1H4ALOX5 | |
| SCHEMBL7401422 | 0.79 | LMNA (0.71) | L3MBTL1LMNAALDH1A1NR1H4ALOX5 | |
| SCHEMBL5358921 | 0.79 | LMNA (0.60) | L3MBTL1LMNAALDH1A1NR1H4ALOX5 | |
| SCHEMBL2716599 | 0.78 | LMNA (0.68) | L3MBTL1LMNAALDH1A1NR1H4ALOX5 | |
| SCHEMBL6544287 | 0.78 | MEN1 (0.47) | L3MBTL1LMNAALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11606393 | 0.77 | LMNA (0.66) | L3MBTL1LMNAALOX5RAB9ASMN1; SMN2 | |
| SCHEMBL12191319 | 0.76 | SMN1; SMN2 (0.46) | L3MBTL1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL232540 | 0.76 | LMNA (0.59) | L3MBTL1LMNAALDH1A1NR1H4ALOX5 | |
| SCHEMBL12616728 | 0.76 | LMNA (0.55) | L3MBTL1LMNAALDH1A1NR1H4ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910331-A1 | PYRAZOLE DERIVATIVES AS CBl MODULATORS | AstraZeneca AB (SE) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007010217-A1 | PYRAZOLE DERIVATIVES AS CBl MODULATORS | ASTRAZENECA AB (SE) | 2007-01-25 | — | — | WO | disclosed |