Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3820164 | 0.84 | KMT2A (0.50) | ALDH1A1LMNA | |
| SCHEMBL4600612 | 0.81 | L3MBTL1 (0.58) | NR1H4ALDH1A1L3MBTL1LMNAALOX5 | |
| SCHEMBL2716599 | 0.78 | LMNA (0.68) | NR1H4ALDH1A1L3MBTL1LMNAFFAR1 | |
| SCHEMBL8871420 | 0.77 | LMNA (0.64) | NR1H4ALDH1A1L3MBTL1LMNAPPARG | |
| SCHEMBL7401422 | 0.77 | LMNA (0.71) | NR1H4ALDH1A1L3MBTL1LMNAFFAR1 | |
| SCHEMBL28123460 | 0.77 | LOXL2 (0.37) | LMNA | |
| SCHEMBL8742386 | 0.76 | GAA (0.46) | ALDH1A1L3MBTL1LMNAPPARA | |
| SCHEMBL30558126 | 0.76 | KMT2A (0.51) | ALDH1A1L3MBTL1LMNA | |
| SCHEMBL30100604 | 0.76 | LMNA (0.51) | ALDH1A1L3MBTL1LMNA | |
| SCHEMBL27973452 | 0.76 | LMNA (0.65) | NR1H4ALDH1A1L3MBTL1LMNAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |