Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582132 | 0.82 | DRD1 (0.34) | DRD1NPSR1 | |
| SCHEMBL4582874 | 0.81 | TYMP (0.38) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL3617725 | 0.80 | TYMP (0.39) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL4584726 | 0.75 | TYMP (0.45) | DRD1ALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL4583927 | 0.72 | TYMP (0.47) | DRD1ALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL4608946 | 0.71 | TYMP (0.46) | ALDH1A1HPGDKDM4EKMT2AHSD17B10 | |
| SCHEMBL4582299 | 0.70 | NPSR1 (0.37) | DRD1NPSR1 | |
| SCHEMBL2452085 | 0.69 | TYMP (0.46) | ALDH1A1HPGDKDM4EKMT2AHSD17B10 | |
| SCHEMBL29039021 | 0.65 | SMN1; SMN2 (0.38) | ALDH1A1HPGDKDM4EKMT2AGAA | |
| SCHEMBL4582844 | 0.64 | HSD11B1 (0.41) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972623-A1 | Arylpyridazines as fungicides | Bayer CropScience AG (DE) | 2008-09-24 | — | — | EP | disclosed |