Tepa

Tepa

SCHEMBL4600770

NCCCO.O=P(N1CC1)(N1CC1)N1CC1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BLM P54132 3/20 0.36
LMNA P02545 2/20 0.36
CYP3A4 P08684 1/20 0.36
NFKB1 P19838 1/20 0.36
PMP22 Q01453 1/20 0.36
GABBR2 O75899 3/20 0.33
GABBR1 Q9UBS5 3/20 0.33
TSHR P16473 2/20 0.33
CYP1A2 P05177 1/20 0.33
THPO P40225 1/20 0.33
FDPS P14324 2/20 0.31
PDE3A Q14432 1/20 0.31
DRD3 P35462 1/20 0.31
ALDH1A1 P00352 1/20 0.30
GABRR1 P24046 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL6535607 0.75 BLM (0.52) BLMLMNACYP3A4NFKB1PMP22
Phosphoric Acid SCHEMBL27481355 0.75 BLM (0.52) BLMLMNACYP3A4NFKB1PMP22
Tepa SCHEMBL11572 0.71 ABCB11 (0.38) LMNACYP3A4DRD3
SCHEMBL17028873 0.71 TSHR (0.58) BLMLMNACYP3A4NFKB1PMP22
SCHEMBL16933 0.71
SCHEMBL11047830 0.68
SCHEMBL11561593 0.68
Ammonia Solution, Strong SCHEMBL8368397 0.68
Water SCHEMBL10698036 0.68
Water SCHEMBL5930812 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1913046-A1 METHOD FOR REDUCING THE CONCENTRATION OF ISOCYANATES Sunflower S.r.l. (IT) 2008-04-23 EP disclosed
WO-2007015276-A1 METHOD FOR REDUCING THE CONCENTRATION OF ISOCYANATES SUNFLOWER S.R.L. (IT) 2007-02-08 WO disclosed