Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 known ✓ | P13945 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.48 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 5/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL27481355 | 1.00 | BLM (0.52) | BLMLMNACYP3A4NFKB1PMP22 | |
| Phosphoric Acid SCHEMBL27508186 | 0.91 | LMNA (0.50) | BLMLMNACYP3A4NFKB1PMP22 | |
| Phosphoric Acid SCHEMBL3918672 | 0.88 | FDPS (0.48) | BLMLMNACYP3A4NFKB1PMP22 | |
| Phosphoric Acid SCHEMBL28144890 | 0.88 | FDPS (0.48) | BLMLMNACYP3A4NFKB1PMP22 | |
| SCHEMBL8949690 | 0.84 | GABBR2 (0.52) | BLMLMNACYP3A4NFKB1PMP22 | |
| Phosphoric Acid SCHEMBL1832300 | 0.83 | ALDH1A1 (0.61) | BLMLMNACYP3A4NFKB1PMP22 | |
| Putrescine SCHEMBL2541172 | 0.83 | LMNA (0.61) | BLMLMNACYP3A4NFKB1PMP22 | |
| Phosphoric Acid SCHEMBL1831539 | 0.83 | ALDH1A1 (0.61) | BLMLMNACYP3A4NFKB1PMP22 | |
| Phosphoric Acid SCHEMBL63996 | 0.83 | — | — | |
| Phosphoric Acid SCHEMBL64139 | 0.83 | ALDH1A1 (0.61) | BLMLMNACYP3A4NFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116375903-B | Preparation method of natural pseudo-ginseng polysaccharide and preparation method of Pickering emulsion | 南京林业大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-114934086-B | Method for producing natural protein/polysaccharide composite nano-particles by using lactobacillus plantarum | 南京林业大学 | 2023-08-15 | — | — | CN | disclosed |
| CN-115232287-B | Flame-retardant slow-rebound polyurethane sponge and preparation method thereof | 南京金栖化工集团有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-116375903-A | Preparation method of natural pseudo-ginseng polysaccharide and preparation method of Pickering emulsion | 南京林业大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-115232287-A | Flame-retardant slow-rebound polyurethane sponge and preparation method thereof | 南京金栖化工集团有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-114934086-A | Method for producing natural protein/polysaccharide composite nano-particles by using lactobacillus plantarum | 南京林业大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-100528127-C | Nanometer skin-activating emulsion cosmetics and its preparation process | NORTHWEST AGRICULTURAL & FORES (CN) | 2009-08-19 | — | — | CN | disclosed |
| CN-1931122-A | Nanometer skin-activating emulsion cosmetics and its prepn process | NORTHWEST AGRICULTURAL & FORES (CN) | 2007-03-21 | — | — | CN | disclosed |
| CN-1492755-A | Water-in-stable kojic acid derivatives and method for preparing thereof, and whitening cosmetic composition containing same | 株式会社太平洋 | 2004-04-28 | — | — | CN | disclosed |
| EP-1372594-A4 | WATER-IN-STABLE KOJIC ACID DERIVATIVES AND METHOD FOR PREPARING THEREOF, AND WHITENING COSMETICS COMPOSITION CONTAINING THE SAME | AMOREPACIFIC CORP (KR) | 2004-04-07 | — | — | EP | disclosed |
| EP-1372594-A1 | WATER-IN-STABLE KOJIC ACID DERIVATIVES AND METHOD FOR PREPARING THEREOF, AND WHITENING COSMETICS COMPOSITION CONTAINING THE SAME | Amorepacific Corporation (KR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002083092-A1 | WATER-IN-STABLE KOJIC ACID DERIVATIVES AND METHOD FOR PREPARING THEREOF, AND WHITENING COSMETICS COMPOSITION CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2002-10-24 | — | — | WO | disclosed |