Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GABBR2 | O75899 | 4/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5864212 | 0.81 | TAAR1 (0.54) | SMN1; SMN2TDP1CYP2C9LMNACYP2D6 | |
| SCHEMBL4483465 | 0.81 | TAAR1 (0.54) | SMN1; SMN2TDP1CYP2C9LMNACYP2D6 | |
| SCHEMBL4483463 | 0.81 | TAAR1 (0.54) | SMN1; SMN2TDP1CYP2C9LMNACYP2D6 | |
| SCHEMBL2386276 | 0.81 | GABBR2 (0.57) | POLBSMN1; SMN2TDP1GABBR2GABBR1 | |
| SCHEMBL186610 | 0.80 | GABBR2 (0.55) | SMN1; SMN2GABBR2GABBR1LMNACYP2D6 | |
| SCHEMBL904490 | 0.80 | GABBR2 (0.55) | SMN1; SMN2GABBR2GABBR1LMNACYP2D6 | |
| SCHEMBL904476 | 0.80 | GABBR2 (0.55) | SMN1; SMN2GABBR2GABBR1LMNACYP2D6 | |
| SCHEMBL31037721 | 0.80 | CYP2C19 (0.45) | POLBTDP1GABBR2GABBR1CYP2C9 | |
| SCHEMBL8770912 | 0.79 | KMT2A (0.42) | MEN1KMT2ACYP1A2CNR2 | |
| SCHEMBL1503961 | 0.79 | GABBR2 (0.59) | POLBGABBR2GABBR1CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910270-A2 | COMPOUNDS AND THEIR SALTS SPECIFIC TO THE PPAR RECEPTORS AND THE EGF RECEPTORS AND THEIR USE IN THE MEDICAL FIELD | Giuliani International Limited (IE) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007010516-A2 | COMPOUNDS AND THEIR SALTS SPECIFIC TO THE PPAR RECEPTORS AND THE EGF RECEPTORS AND THEIR USE IN THE MEDICAL FIELD | GIULIANI INTERNATIONAL LIMITED (IE) | 2007-01-25 | — | — | WO | disclosed |