Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23080109 | 0.82 | L3MBTL1 (0.46) | KMT2ACYP1A2MEN1L3MBTL1 | |
| SCHEMBL3675113 | 0.82 | CYP1A2 (0.50) | CYP1A2 | |
| SCHEMBL28757378 | 0.82 | CYP1A2 (0.50) | CYP1A2 | |
| SCHEMBL657687 | 0.81 | FNTA (0.54) | KMT2ACYP1A2MEN1 | |
| SCHEMBL4483465 | 0.81 | TAAR1 (0.54) | CYP1A2 | |
| SCHEMBL4483463 | 0.81 | TAAR1 (0.54) | CYP1A2 | |
| SCHEMBL5864212 | 0.81 | TAAR1 (0.54) | CYP1A2 | |
| SCHEMBL186610 | 0.80 | GABBR2 (0.55) | L3MBTL1 | |
| SCHEMBL904490 | 0.80 | GABBR2 (0.55) | L3MBTL1 | |
| SCHEMBL904476 | 0.80 | GABBR2 (0.55) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020445-B1 | FUSED PYRIDINE DERIVATIVES | EISAI R&D MAN CO LTD (JP) | 2008-08-13 | — | — | EP | disclosed |
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |