Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12071765 | 0.94 | TSHR (0.33) | TSHRPOLBHTT | |
| SCHEMBL12070325 | 0.93 | TSHR (0.36) | TSHRPOLBHTT | |
| SCHEMBL45930 | 0.93 | L3MBTL1 (0.32) | HTT | |
| SCHEMBL12070324 | 0.93 | TSHR (0.39) | TSHRPOLBHTTADAM17 | |
| SCHEMBL19139449 | 0.92 | TSHR (0.36) | TSHRPOLBHTT | |
| SCHEMBL46212 | 0.88 | TSHR (0.35) | TSHR | |
| SCHEMBL12070326 | 0.87 | TSHR (0.33) | TSHRPOLBHTT | |
| SCHEMBL37306 | 0.87 | MDM2 (0.33) | TSHRPOLBHTT | |
| SCHEMBL46209 | 0.87 | TSHR (0.33) | TSHR | |
| SCHEMBL46261 | 0.87 | TP53 (0.32) | TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9485989-B2 | Method of controlling neonicotinoid resistant hemiptera | SYNGENTA PARTICIPATIONS AG (CH) | 2016-11-08 | — | — | US | disclosed |
| US-9485989-B2 | Method of controlling neonicotinoid resistant hemiptera | SYNGENTA PARTICIPATIONS AG (CH) | 2016-11-08 | — | — | US | disclosed |
| US-9462808-B2 | Pesticidal compositions | SYNGENTA PARTICIPANTS AG (CH) | 2016-10-11 | — | — | US | disclosed |
| US-9462808-B2 | Pesticidal compositions | SYNGENTA PARTICIPANTS AG (CH) | 2016-10-11 | — | — | US | disclosed |
| EP-2575449-B1 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-04-27 | — | — | EP | disclosed |
| US-9018135-B2 | Pesticidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2015-04-28 | — | — | US | disclosed |
| US-9018135-B2 | Pesticidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2015-04-28 | — | — | US | disclosed |
| US-20140057930-A1 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-27 | — | — | US | disclosed |
| US-20140057930-A1 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-27 | — | — | US | disclosed |
| US-20140018242-A1 | METHOD OF CROP ENHANCEMENT | SYNGENTA PARTICIPATIONS AG (CH) | 2014-01-16 | — | — | US | disclosed |
| EP-2352376-B1 | SPIROHETEROCYCLIC N-OXYAMIDES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-01-01 | — | — | EP | disclosed |
| US-20130225411-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130225411-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130150394-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-13 | — | — | US | disclosed |
| WO-2011151249-A2 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151247-A2 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151248-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| US-20110224079-A1 | SPIROHETEROCYCLIC N-OXYAMIDES AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-09-15 | — | — | US | disclosed |
| US-20110224079-A1 | SPIROHETEROCYCLIC N-OXYAMIDES AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-09-15 | — | — | US | disclosed |
| WO-2010063670-A1 | SPIROHETEROCYCLIC N-OXYAMIDES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150394-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, GAP43 | TSHR 1200/4885POLB 4095/4885HTT 3129/4885 |
| US-20130225411-A1 | PESTICIDAL COMPOSITIONS | DDT, CIP2A, CYP51A1 | TSHR 458/4885POLB 2598/4885HTT 4528/4885 |
| US-20140018242-A1 | METHOD OF CROP ENHANCEMENT | MYB, GUSB, CHAT | TSHR 4598/4885POLB 2397/4885HTT 4026/4885 |
| US-20140057930-A1 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | DDT, NAMPT, NISCH | TSHR 1645/4885POLB 2560/4885HTT 737/4885 |
| US-20110224079-A1 | SPIROHETEROCYCLIC N-OXYAMIDES AS PESTICIDES | DDT, ODC1, ACHE | TSHR 2206/4885POLB 4547/4885HTT 2955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.