Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 5/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3212927 | 0.91 | RAB9A (0.56) | RAB9ACYP1A2CYP3A4CYP2C19HPGD | |
| SCHEMBL4601009 | 0.83 | SMN1; SMN2 (0.54) | RAB9ACYP1A2CYP3A4CYP2C19HPGD | |
| SCHEMBL8635319 | 0.82 | RAB9A (0.66) | RAB9ACYP1A2CYP3A4CYP2C19HPGD | |
| SCHEMBL3205492 | 0.82 | PPARG (0.51) | CYP1A2CYP3A4CYP2C19HPGDLMNA | |
| SCHEMBL3219568 | 0.81 | PPARG (0.62) | CYP1A2CYP3A4CYP2C19HPGDLMNA | |
| SCHEMBL3204740 | 0.80 | PPARG (0.53) | RAB9ALMNASMN1; SMN2PPARG | |
| SCHEMBL3220986 | 0.79 | RAB9A (0.58) | RAB9ACYP1A2CYP3A4CYP2C19HPGD | |
| SCHEMBL5687596 | 0.77 | RAB9A (0.73) | RAB9ACYP1A2CYP3A4CYP2C19HPGD | |
| SCHEMBL31251923 | 0.77 | RAB9A (0.73) | RAB9ACYP1A2CYP3A4CYP2C19HPGD | |
| SCHEMBL3751730 | 0.77 | CYP1A2 (0.56) | RAB9ACYP1A2CYP3A4CYP2C19HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041892-A1 | Therapeutic agent for diabetes | ABE HIDENORI | 2010-02-18 | — | — | US | disclosed |
| US-20090270631-A1 | Therapeutic agent for diabetes | ABE HIDENORI | 2009-10-29 | — | — | US | disclosed |
| US-20080009530-A1 | Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270631-A1 | Therapeutic agent for diabetes | FABP4, SLC5A1, SLC5A2 | RAB9A 3599/4885CYP1A2 2418/4885CYP3A4 3701/4885 |
| US-20080009530-A1 | Therapeutic Agent for Diabetes | FABP4, SLC5A1, SLC5A2 | RAB9A 3729/4885CYP1A2 1645/4885CYP3A4 3275/4885 |
| US-20100041892-A1 | Therapeutic agent for diabetes | FABP4, SLC5A1, SLC5A2 | RAB9A 3599/4885CYP1A2 2418/4885CYP3A4 3701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.