Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30925001 | 0.89 | NPC1 (0.70) | NPC1RAB9AMAPTCYP1A2CYP3A4 | |
| SCHEMBL2789108 | 0.89 | NPC1 (0.70) | NPC1RAB9AMAPTCYP1A2CYP3A4 | |
| Propiolactone SCHEMBL5190919 | 0.82 | MAPT (0.48) | NPC1RAB9AMAPTCYP1A2CYP3A4 | |
| SCHEMBL8091142 | 0.77 | MAPT (0.56) | NPC1RAB9AMAPTCYP1A2CYP3A4 | |
| SCHEMBL25613275 | 0.76 | NPC1 (0.55) | NPC1RAB9AMAPTCYP1A2CYP3A4 | |
| Propiolactone SCHEMBL6691395 | 0.76 | NPC1 (0.79) | NPC1RAB9AMAPTCYP1A2CYP3A4 | |
| SCHEMBL31157858 | 0.73 | NPC1 (1.00) | NPC1RAB9AMAPTCYP1A2CYP3A4 | |
| SCHEMBL22161850 | 0.73 | NPC1 (0.74) | NPC1RAB9AMAPTCYP1A2CYP3A4 | |
| SCHEMBL27636034 | 0.73 | MAPT (0.54) | NPC1RAB9AMAPTCYP1A2CYP3A4 | |
| SCHEMBL4306920 | 0.73 | NPC1 (1.00) | NPC1RAB9AMAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902019-A1 | SULPHONIUM SALT INITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2008-03-26 | — | — | EP | disclosed |
| EP-1789188-A2 | PROCESS FOR THE PHOTOACTIVATION AND USE OF A CATALYST BY AN INVERTED TWO-STAGE PROCEDURE | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-05-30 | — | — | EP | disclosed |
| WO-2007003507-A1 | SULPHONIUM SALT INITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-01-11 | — | — | WO | disclosed |
| WO-2006008251-A2 | PROCESS FOR THE PHOTOACTIVATION AND USE OF A CATALYST BY AN INVERTED TWO-STAGE PROCEDURE | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-01-26 | — | — | WO | disclosed |