⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4607365 | 0.75 | PDE9A (0.32) | — | |
| SCHEMBL31205162 | 0.68 | — | — | |
| SCHEMBL31520298 | 0.66 | — | — | |
| SCHEMBL1126348 | 0.65 | NPC1 (0.32) | — | |
| SCHEMBL25961290 | 0.64 | PDK2 (0.33) | — | |
| SCHEMBL28402482 | 0.62 | LMNA (0.33) | — | |
| SCHEMBL28046787 | 0.62 | CCR1 (0.33) | — | |
| SCHEMBL12245773 | 0.61 | — | — | |
| Methane SCHEMBL28929550 | 0.61 | POLB (0.31) | — | |
| SCHEMBL30600330 | 0.59 | HSD11B1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931337-A2 | PHENYL- AND PYRIDINYL- 1, 2 , 4 - OXADIAZOLONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | Sanofi-Aventis (FR) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007039177-A2 | PHENYL- AND PYRIDINYL- 1, 2 , 4 - OXADIAZOLONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (DE) | 2007-04-12 | — | — | WO | disclosed |