Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 10/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24308304 | 0.74 | LMNA (0.49) | MAPTRXFP1CA12CA1CA2 | |
| SCHEMBL461117 | 0.72 | HSP90AA1 (0.69) | HSP90AA1MAPTEGFRNOX4ALDH1A1 | |
| SCHEMBL460121 | 0.72 | KDM4C (0.42) | MAPTEGFRNOX4ALDH1A1KDM4C | |
| SCHEMBL8929781 | 0.72 | HPGD (0.58) | MAPTRXFP1ALDH1A1LMNAPOLB | |
| SCHEMBL6362855 | 0.71 | LMNA (0.50) | MAPTRXFP1ALDH1A1LMNAPOLB | |
| SCHEMBL11017289 | 0.71 | LMNA (0.46) | MAPTRXFP1CA12CA1CA2 | |
| SCHEMBL9198278 | 0.70 | MAPT (0.46) | MAPTRXFP1ALDH1A1LMNAPOLB | |
| SCHEMBL8930021 | 0.70 | ALDH1A1 (0.47) | MAPTRXFP1ALDH1A1LMNAPOLB | |
| SCHEMBL9197072 | 0.70 | F2R (0.55) | MAPTALDH1A1LMNAHPGD | |
| SCHEMBL9198195 | 0.70 | LMNA (0.49) | MAPTRXFP1ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021519-A1 | EFFICIENT INDUCTION OF PLURIPOTENT STEM CELLS USING SMALL MOLECULE COMPOUNDS | PRESIDENTS AND FELLOWS OF HARVARD COLLEGE (US) | 2012-01-26 | — | — | US | disclosed |
| WO-2010033906-A2 | EFFICIENT INDUCTION OF PLURIPOTENT STEM CELLS USING SMALL MOLECULE COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-03-25 | — | — | WO | disclosed |