Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.55 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.55 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2953697 | 0.87 | ESR1 (0.69) | ESR1ESR2CYP3A4ALDH1A1BLM | |
| SCHEMBL2416999 | 0.80 | ESR1 (0.60) | ESR1ESR2CYP3A4ALDH1A1BLM | |
| Bisphenol A SCHEMBL27648135 | 0.79 | ESR1 (0.55) | ESR1ESR2PDCD1CD274CYP3A4 | |
| SCHEMBL2417003 | 0.78 | ESR1 (0.57) | ESR1ESR2CYP3A4ALDH1A1BLM | |
| SCHEMBL237249 | 0.78 | ESR1 (0.57) | ESR1ESR2CYP3A4ALDH1A1BLM | |
| SCHEMBL7124669 | 0.77 | ESR1 (0.70) | ESR1ESR2PDCD1CD274CYP3A4 | |
| SCHEMBL7919913 | 0.77 | ESR1 (0.70) | ESR1ESR2PDCD1CD274CYP3A4 | |
| Bisphenol A SCHEMBL27987462 | 0.77 | ESR1 (0.70) | ESR1ESR2PDCD1CD274CYP3A4 | |
| SCHEMBL12721606 | 0.77 | ESR1 (0.70) | ESR1ESR2PDCD1CD274CYP3A4 | |
| SCHEMBL4905749 | 0.77 | ESR1 (0.70) | ESR1ESR2PDCD1CD274CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2883899-B1 | METHOD FOR PRODUCING BRANCHED AROMATIC POLYCARBONATE RESIN | MITSUBISHI GAS CHEMICAL CO (JP) | 2016-12-28 | — | — | EP | disclosed |
| EP-2883899-A1 | METHOD FOR PRODUCING BRANCHED AROMATIC POLYCARBONATE RESIN | Mitsubishi Gas Chemical Company, Inc. (JP) | 2015-06-17 | — | — | EP | disclosed |
| EP-0905184-B1 | Aromatic polycarbonate resin composition | GEN ELECTRIC (US) | 2008-04-23 | — | — | EP | disclosed |
| US-7112645-B2 | polycarbonate that has low levels of ionic species, unreacted monomers and small molecule side products which can be detrimental to the taste and other organoleptic properties of food and beverages residing in containers made of polycarbonate | GENERAL ELECTRIC COMPANY (US) | 2006-09-26 | — | — | US | disclosed |
| EP-1191064-B1 | AROMATIC POLYCARBONATE COMPOSITION | TEIJIN LTD (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-20050209434-A1 | polycarbonate that has low levels of ionic species, unreacted monomers and small molecule side products which can be detrimental to the taste and other organoleptic properties of food and beverages residing in containers made of polycarbonate | CITIBANK, N.A., AS COLLATERAL AGENT | 2005-09-22 | — | — | US | disclosed |
| US-6900354-B2 | 3-phenyl-propionamido, 3-phenyl-acrylamido and 3-phenyl-propynamido derivatives | HOFFMAN-LA ROCHE INC. (US) | 2005-05-31 | — | — | US | disclosed |
| EP-1523469-A1 | CINNAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-04-20 | — | — | EP | disclosed |
| EP-0926181-B1 | Manufacturing method for polycarbonate | GEN ELECTRIC (US) | 2004-03-17 | — | — | EP | disclosed |
| US-20040034096-A1 | 3-Phenyl-propionamido, 3-phenyl-acrylamido and 3-phenyl-propynamido derivatives | HOFFMANN-LA ROCHE INC. | 2004-02-19 | — | — | US | disclosed |
| EP-0905178-A1 | Aromatic polycarbonate resin composition | GENERAL ELECTRIC COMPANY (US) | 1999-03-31 | — | — | EP | disclosed |
| EP-0572225-B1 | Polycarbonate containing thermosetting resin compositions with low shrinkage | GE PLASTICS JAPAN LTD (JP) | 1997-12-10 | — | — | EP | disclosed |
| US-5606008-A | MELT CONDENSATION POLYMERIZATION OF AROMATIC DIHYDROXY COMPOUND AND ESTER IN THE PRESENCE OF ALIPHATIC AMINE AND ALKALI OR ALKALINE EARTH METAL COMPOUND | GENERAL ELECTRIC COMPANY (US) | 1997-02-25 | — | — | US | disclosed |
| US-5502153-A | MELT POLYMERIZATION AROMATIC DIHYDROXY COMPOUNDS AND DIESTER CARBONATES IN THE PRESENCE OF A CATALYST AND STABILIZERS | GE PLASTICS JAPAN LTD. (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5489655-A | CONTAINING POLYCARBONATE DERIVED FROM AROMATIC DIHYDROXY COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 1996-02-06 | — | — | US | disclosed |
| US-5418269-A | Made by ester interchange, mold release, thermal stability, little discoloration on molding, disks | GE PLASTICS JAPAN (JP) | 1995-05-23 | — | — | US | disclosed |
| US-5364926-A | Preparing method of polycarbonate resin compounds for the optical use | GE PLASTICS, JAPAN, LTD. (GEP) (JP) | 1994-11-15 | — | — | US | disclosed |
| EP-0615996-A1 | Method for preparing optical-grade polycarbonate compositions | GE PLASTICS JAPAN LIMITED (JP) | 1994-09-21 | — | — | EP | disclosed |
| EP-0572225-A1 | Polycarbonate containing thermosetting resin compositions with low shrinkage | GE PLASTICS JAPAN LIMITED (JP) | 1993-12-01 | — | — | EP | disclosed |
| EP-0561638-A1 | Optical-grade polycarbonate resin compositions | GE PLASTICS JAPAN LIMITED (JP) | 1993-09-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034096-A1 | 3-Phenyl-propionamido, 3-phenyl-acrylamido and 3-phenyl-propynamido derivatives | MAOB, MAOA, APP | ESR1 2377/4885ESR2 1911/4885PDCD1 2702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.