SCHEMBL4601383

SCHEMBL4601383

CC(C)CC(O)(CC(N)=O)C(N)=O

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
FDPS P14324 1/20 0.33
GRM2 Q14416 1/20 0.30
GRM3 Q14832 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22433277 0.80 GAA (0.35) GAASMN1; SMN2
SCHEMBL6344934 0.80 GAA (0.36) GAASMN1; SMN2FDPSGRM2GRM3
SCHEMBL30700115 0.80 GAA (0.36) GAASMN1; SMN2FDPSGRM2GRM3
SCHEMBL30700093 0.80 GAA (0.36) GAASMN1; SMN2FDPSGRM2GRM3
SCHEMBL1574132 0.78 ALDH1A1 (0.35)
SCHEMBL7907381 0.73 KDM4E (0.33) FDPSGRM2GRM3
SCHEMBL28743867 0.72 FDPS (0.33) GAASMN1; SMN2FDPSGRM2GRM3
SCHEMBL8633404 0.70 AR (0.33) GAASMN1; SMN2FDPSGRM2GRM3
SCHEMBL20049737 0.70 GRM2 (0.36) GRM2GRM3
SCHEMBL21079068 0.70 GRM2 (0.36) GAASMN1; SMN2FDPSGRM2GRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1915342-A1 A NOVEL HYDROXAMIC ACID DERIVATIVE AS PEPTIDE DEFORMYLASE INHIBITOR AND MANUFACTURING METHOD THEREOF Ildong Pharmaceutical Co., Ltd. (KR) 2008-04-30 EP disclosed
WO-2006115353-A1 A NOVEL HYDROXAMIC ACID DERIVATIVE AS PEPTIDE DEFORMYLASE INHIBITOR AND MANUFACTURING METHOD THEREOF ILDONG PHARMACEUTICAL CO., LTD. (KR) 2006-11-02 WO disclosed