Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.46 |
| ▸ | MMP9 | P14780 | 6/20 | 0.46 |
| ▸ | MMP8 | P22894 | 3/20 | 0.46 |
| ▸ | ECE1 | P42892 | 3/20 | 0.44 |
| ▸ | MMP1 | P03956 | 6/20 | 0.43 |
| ▸ | MMP3 | P08254 | 5/20 | 0.43 |
| ▸ | MMP14 | P50281 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | FCER2 | P06734 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | MMP7 | P09237 | 2/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601655 | 0.82 | MMP2 (0.65) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL743997 | 0.79 | SLC1A3 (0.43) | MMESLC1A3SLC1A2KISS1R | |
| SCHEMBL1650677 | 0.79 | SLC1A3 (0.43) | MMESLC1A3SLC1A2KISS1R | |
| SCHEMBL20548024 | 0.77 | SLC1A3 (0.57) | MMESLC1A3SLC1A2 | |
| SCHEMBL7094101 | 0.77 | SLC1A3 (0.57) | MMESLC1A3SLC1A2 | |
| SCHEMBL7099858 | 0.76 | MME (0.53) | MMESLC1A3SLC1A2 | |
| SCHEMBL27813272 | 0.74 | ECE1 (0.49) | MMP2MMP8ECE1MMP3HDAC7 | |
| SCHEMBL6690561 | 0.73 | SLC1A3 (0.39) | MMESLC1A3SLC1A2KISS1R | |
| SCHEMBL21896208 | 0.73 | SLC1A3 (0.36) | MMESLC1A3SLC1A2 | |
| SCHEMBL6690558 | 0.72 | SLC1A3 (0.38) | MMP9MMP1MMP3MMESLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915342-A1 | A NOVEL HYDROXAMIC ACID DERIVATIVE AS PEPTIDE DEFORMYLASE INHIBITOR AND MANUFACTURING METHOD THEREOF | Ildong Pharmaceutical Co., Ltd. (KR) | 2008-04-30 | — | — | EP | disclosed |
| WO-2006115353-A1 | A NOVEL HYDROXAMIC ACID DERIVATIVE AS PEPTIDE DEFORMYLASE INHIBITOR AND MANUFACTURING METHOD THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2006-11-02 | — | — | WO | disclosed |