Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 12/20 | 0.65 |
| ▸ | MMP9 | P14780 | 11/20 | 0.65 |
| ▸ | MMP8 | P22894 | 7/20 | 0.65 |
| ▸ | MMP1 | P03956 | 13/20 | 0.59 |
| ▸ | MMP3 | P08254 | 9/20 | 0.59 |
| ▸ | MMP14 | P50281 | 3/20 | 0.59 |
| ▸ | MMP13 | P45452 | 3/20 | 0.59 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.59 |
| ▸ | MMP7 | P09237 | 4/20 | 0.52 |
| ▸ | MMP12 | P39900 | 2/20 | 0.52 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.51 |
| ▸ | FCER2 | P06734 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872686 | 0.88 | MMP2 (0.76) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL8269110 | 0.83 | MME (0.61) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL4288816 | 0.82 | MMP2 (0.63) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL6856648 | 0.82 | MME (0.56) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL8890070 | 0.82 | MMP2 (0.54) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL7426952 | 0.82 | MMP2 (0.54) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL4601386 | 0.82 | MMP2 (0.46) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL7763152 | 0.81 | MMP2 (0.75) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL20198726 | 0.81 | MMP2 (0.61) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL10424070 | 0.79 | MMP2 (0.52) | MMP2MMP9MMP8MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821668-A1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITOR | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-02-04 | — | — | EP | claimed |
| WO-1996033165-A1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITOR | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-10-24 | — | — | WO | claimed |
| EP-0821668-A1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITOR | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033165-A1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITOR | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-10-24 | — | — | WO | disclosed |