Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PHGDH | O43175 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23340098 | 0.83 | ADRA2A (0.54) | ADRA2AADRA2BADRA2CMEN1KMT2A | |
| SCHEMBL576814 | 0.81 | LMNA (0.67) | MEN1KMT2AMAPTTSHRUSP2 | |
| SCHEMBL164538 | 0.81 | LMNA (0.67) | MEN1KMT2AMAPTTSHRUSP2 | |
| SCHEMBL385012 | 0.81 | — | — | |
| SCHEMBL576454 | 0.81 | LMNA (0.67) | MEN1KMT2AMAPTTSHRUSP2 | |
| SCHEMBL16924853 | 0.81 | LMNA (0.67) | MEN1KMT2AMAPTTSHRUSP2 | |
| SCHEMBL4624722 | 0.80 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CMEN1KMT2A | |
| SCHEMBL4624730 | 0.80 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CMEN1KMT2A | |
| SCHEMBL8584033 | 0.80 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CMEN1KMT2A | |
| SCHEMBL8584036 | 0.80 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8574420-B2 | Ultrathin multilayered films for controlled release of anionic reagents | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-11-05 | — | — | US | disclosed |
| US-20120065616-A1 | Ultrathin Multilayered Films for Controlled Release of Anionic Reagents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-03-15 | — | — | US | disclosed |