Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.47 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4624722 | 1.00 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CRAD52ATM | |
| SCHEMBL4624728 | 1.00 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CRAD52ATM | |
| SCHEMBL8584033 | 1.00 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CRAD52ATM | |
| SCHEMBL4624730 | 1.00 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CRAD52ATM | |
| SCHEMBL23340098 | 0.85 | ADRA2A (0.54) | ADRA2AADRA2BADRA2CRAD52ATM | |
| SCHEMBL460139 | 0.80 | ADRA2A (0.58) | ADRA2AADRA2BADRA2CATMMAPT | |
| SCHEMBL1099464 | 0.80 | KDM4E (0.66) | ADRA2AADRA2BADRA2CATMMAPT | |
| SCHEMBL4252814 | 0.77 | KDM4E (0.50) | ADRA2AADRA2BADRA2CRAD52ATM | |
| SCHEMBL21361603 | 0.77 | KDM4E (0.50) | ADRA2AADRA2BADRA2CRAD52ATM | |
| SCHEMBL10671655 | 0.77 | KDM4E (0.50) | ADRA2AADRA2BADRA2CRAD52ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808069-A | Salts of 2-(3-benzoylphenyl) propionic acid with organic bases and pharmaceutical compositions thereof | DOMPE' FARMACEUTICI SPA (IT) | 1998-09-15 | — | — | US | disclosed |