Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | STAT6 | P42226 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4474836 | 0.75 | PPP5C (0.30) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL7553800 | 0.69 | MAPK1 (0.33) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL28886822 | 0.66 | LMNA (0.33) | MAPK1CYP2C19THPOLMNAPMP22 | |
| SCHEMBL31568085 | 0.64 | HSD11B1 (0.37) | — | |
| SCHEMBL28756584 | 0.63 | — | — | |
| SCHEMBL4315892 | 0.61 | LMNA (0.34) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL24785431 | 0.60 | LMNA (0.34) | CYP2C19THPOLMNA | |
| SCHEMBL571727 | 0.60 | LMNA (0.36) | CYP2C19LMNAMTOR | |
| SCHEMBL24786028 | 0.60 | LMNA (0.34) | CYP2C19THPOLMNA | |
| SCHEMBL11593269 | 0.60 | LMNA (0.36) | CYP2C19LMNAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0905184-B1 | Aromatic polycarbonate resin composition | GEN ELECTRIC (US) | 2008-04-23 | — | — | EP | disclosed |
| US-5973101-A | COMPRISING A STABILIZER DEACTIVATING THE METAL IMPURITY, PREVENTING THE INTERACTION OF HYDROXYL END GROUPS OF POLYCARBONATES WITH METALS | GENERAL ELECTRIC COMPANY (US) | 1999-10-26 | — | — | US | disclosed |
| EP-0905184-A2 | Aromatic polycarbonate resin composition | GENERAL ELECTRIC COMPANY (US) | 1999-03-31 | — | — | EP | disclosed |