Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602506 | 0.89 | MMP2 (0.33) | — | |
| SCHEMBL3218749 | 0.81 | PPARG (0.39) | RAB9ASCN9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4601059 | 0.80 | NPC1 (0.38) | RAB9ASCN9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4602937 | 0.74 | RAB9A (0.39) | RAB9ASCN9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4601430 | 0.73 | SCN9A (0.38) | RAB9ASCN9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3218634 | 0.69 | CNR2 (0.45) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3204951 | 0.68 | FFAR1 (0.54) | RAB9ASCN9ASMN1; SMN2NPC1CASP3 | |
| SCHEMBL4601061 | 0.68 | POLB (0.39) | RAB9ASCN9AHPGDNPC1ALDH1A1 | |
| SCHEMBL3209900 | 0.67 | MAPT (0.55) | RAB9ASCN9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3209916 | 0.67 | MAPT (0.55) | RAB9ASCN9AMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |