Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093026 | 0.86 | ALOX5 (0.53) | MAOBL3MBTL1ALOX5LMNAMEN1 | |
| SCHEMBL2202368 | 0.85 | MAOB (0.58) | MAOBBCHE | |
| SCHEMBL6201987 | 0.84 | MAOB (0.50) | MAOBL3MBTL1ALOX5NPC1LMNA | |
| SCHEMBL3948493 | 0.82 | MAOB (0.58) | MAOBALOX5LMNABCHECYP4F2 | |
| SCHEMBL2772599 | 0.81 | MAOB (0.49) | MAOBL3MBTL1ALOX5LMNABCHE | |
| SCHEMBL15474940 | 0.80 | MAPK1 (0.40) | NPC1KDM4ECHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL15474531 | 0.79 | MAOB (0.48) | MAOBL3MBTL1MEN1KMT2ABCHE | |
| SCHEMBL7295428 | 0.79 | L3MBTL1 (0.44) | MAOBL3MBTL1ALOX5LMNASMN1; SMN2 | |
| SCHEMBL20703590 | 0.77 | MAPK1 (0.42) | L3MBTL1NPC1LMNAKDM4EMEN1 | |
| SCHEMBL7953637 | 0.77 | MAPK1 (0.40) | MAOBL3MBTL1NPC1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101282725-A | Therapeutic agent for diabetes | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2008-10-08 | — | — | CN | disclosed |
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |