Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093026 | 0.88 | ALOX5 (0.53) | MAOBALOX5BCHECYP4F2CYP4A11 | |
| SCHEMBL3948493 | 0.86 | MAOB (0.58) | MAOBALOX5BCHECYP4F2CYP4A11 | |
| SCHEMBL2772599 | 0.85 | MAOB (0.49) | MAOBALOX5BCHECYP4F2CYP4A11 | |
| SCHEMBL4601443 | 0.84 | MAOB (0.45) | MAOBALOX5BCHECYP4F2CYP4A11 | |
| SCHEMBL2202368 | 0.83 | MAOB (0.58) | MAOBBCHE | |
| SCHEMBL29023056 | 0.79 | CCR1 (0.34) | MAOBALDH1A1LMNACYP1A2 | |
| SCHEMBL27581024 | 0.78 | BCHE (0.47) | MAOBALOX5BCHECYP4F2CYP4A11 | |
| SCHEMBL28747010 | 0.78 | MAOB (0.44) | MAOBALOX5BCHECYP4F2CYP4A11 | |
| SCHEMBL27252705 | 0.78 | MAOB (0.74) | MAOBALOX5BCHECYP4F2CYP4A11 | |
| SCHEMBL28010652 | 0.77 | ALOX5 (0.45) | MAOBALOX5BCHECYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100467597-C | Fungal cell wall synthetic genes | EISAI CO LTD (JP) | 2009-03-11 | — | — | CN | disclosed |
| CN-100467598-C | Fungal cell wall synthetic genes | EISAI CO LTD (JP) | 2009-03-11 | — | — | CN | disclosed |
| CN-101285061-A | Fungal cell wall synthetic genes | EISAI R&D MAN CO LTD (JP) | 2008-10-15 | — | — | CN | disclosed |
| CN-1873003-A | Fungal cell wall synthesis gene | EISAI CO LTD (JP) | 2006-12-06 | — | — | CN | disclosed |
| CN-1873002-A | Fungal cell wall synthesis gene | EISAI CO LTD (JP) | 2006-12-06 | — | — | CN | disclosed |
| CN-1249227-C | Fungal cell wall synthetic genes | EISAI CO LTD (JP) | 2006-04-05 | — | — | CN | disclosed |
| EP-1513817-A1 | 1, 2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Pharmaceutical Company Limited (JP) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003099793-A9 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL (JP) | 2005-02-10 | — | — | WO | disclosed |
| WO-2003099793-A1 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-12-04 | — | — | WO | disclosed |
| CN-1449443-A | Fungal cell wall synthetic genes | EISAI CO LTD (JP) | 2003-10-15 | — | — | CN | disclosed |
| EP-1300464-A1 | FUNGAL CELL WALL SYNTHESIS GENE | Eisai Co., Ltd. (JP) | 2003-04-09 | — | — | EP | disclosed |