SCHEMBL4601474

SCHEMBL4601474

Cc1ccccc1N(CCN)c1ccccc1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.43
CARM1 Q86X55 1/20 0.39
PRMT6 Q96LA8 1/20 0.39
PRMT8 Q9NR22 1/20 0.39
ACHE P22303 2/20 0.38
TSHR P16473 1/20 0.38
SIGMAR1 Q99720 1/20 0.37
ALDH1A1 P00352 2/20 0.37
CYP3A4 P08684 3/20 0.35
LMNA P02545 2/20 0.35
TRPM8 Q7Z2W7 1/20 0.35
TP53 P04637 2/20 0.35
TDP1 Q9NUW8 1/20 0.34
HTR7 P34969 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ESR1 P03372 1/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
KIF11 P52732 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3716299 0.88 TAAR1 (0.41) TAAR1CARM1PRMT6PRMT8ACHE
SCHEMBL7186151 0.81 CARM1 (0.42) TAAR1CARM1PRMT6PRMT8ACHE
SCHEMBL11557705 0.78 MAPT (0.44) ACHETSHRSIGMAR1ALDH1A1CYP3A4
SCHEMBL5825063 0.78 TAAR1 (0.39) TAAR1CARM1PRMT6PRMT8ACHE
SCHEMBL28985641 0.76 CARM1 (0.41) TAAR1CARM1PRMT6PRMT8TSHR
SCHEMBL1954433 0.75 TAAR1 (0.41) TAAR1ACHETSHRSIGMAR1ALDH1A1
SCHEMBL30629029 0.75 TAAR1 (0.41) TAAR1ACHETSHRSIGMAR1ALDH1A1
SCHEMBL3682981 0.75 LMNA (0.46) ACHETSHRSIGMAR1ALDH1A1CYP3A4
SCHEMBL8651562 0.74 TAAR1 (0.43) TAAR1CARM1PRMT6PRMT8TSHR
SCHEMBL31314382 0.74 TAAR1 (0.43) TAAR1CARM1PRMT6PRMT8TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1066617-C Flavor enhancing composition containing colloidal silica and method for its preparation and use NOVATECH INC (US) 2001-06-06 CN claimed
EP-0650330-A4 1995-06-07 EP claimed
EP-0650330-A1 FLAVOR ENHANCING COMPOSITION CONTAINING COLLOIDAL SILICA AND METHOD FOR ITS PREPARATION AND USE NOVATECH, INC. (US) 1995-05-03 EP claimed
WO-1994001005-A1 FLAVOR ENHANCING COMPOSITION CONTAINING COLLOIDAL SILICA AND METHOD FOR ITS PREPARATION AND USE NOVATECH, INC. (US) 1994-01-20 WO claimed
CN-107641163-B Composition for removing titanium isoprene rubber catalyst and application thereof 中国石油化工股份有限公司 2020-12-18 CN disclosed
CN-107652462-B Heat energy storage system and preparation method thereof 航天材料及工艺研究所 2020-09-18 CN disclosed
CN-107709619-A Thin corrosion protection coatings containing polyamidoamine polymers 汉高股份有限及两合公司 2018-02-16 CN disclosed
CN-107641163-A Composition and its application for titanium system isoprene rubber catalyst removal 中国石油化工股份有限公司 2018-01-30 CN disclosed
EP-0980882-B1 POLYMERIZABLE UNSATURATED COMPOUNDS, CURABLE RESIN COMPOSITIONS CONTAINING THE SAME, AND PRODUCTS OF CURING THEREOF HUNTSMAN ADV MAT SWITZERLAND (CH) 2008-04-23 EP disclosed
EP-1409564-A4 IMPROVED SPANDEX COMPOSITIONS RADICISPANDEX CORP (US) 2006-05-03 EP disclosed
EP-1409564-A1 IMPROVED SPANDEX COMPOSITIONS RADICISPANDEX CORPORATION (US) 2004-04-21 EP disclosed
CN-1109704-C Polymerizable unsaturated compound, curable resin compositions containing the same, and products of curing thereof VANTIKO AG (CH) 2003-05-28 CN disclosed
EP-0650330-A1 FLAVOR ENHANCING COMPOSITION CONTAINING COLLOIDAL SILICA AND METHOD FOR ITS PREPARATION AND USE NOVATECH, INC. (US) 1995-05-03 EP disclosed
WO-1994001005-A1 FLAVOR ENHANCING COMPOSITION CONTAINING COLLOIDAL SILICA AND METHOD FOR ITS PREPARATION AND USE NOVATECH, INC. (US) 1994-01-20 WO disclosed
US-4886549-A Vat dye and sulfur dye compositions CIBA-GEIEGY CORPORATION (US) 1989-12-12 US disclosed
US-4519805-A Vat dye and sulfur dye compositions CIBA GEIGY CORPORATION (US) 1985-05-28 US disclosed
US-4299759-A HYDROTALCITE ADDITIVES KYOWA CHEMICAL INDUSTRY CO. LTD. (JP) 1981-11-10 US disclosed
US-4247427-A Adhesion promoted block copolyester composition with multi-functional carboxylic compound E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-01-27 US disclosed
US-4156702-A Adhesion promoted block copolyester composition with multi-functional carboxylic compound E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-05-29 US disclosed
US-3969294-A Segmented copolyester adhesives stabilized by alkaline earth oxides and carboxylic compounds E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-07-13 US disclosed