SCHEMBL7186151

SCHEMBL7186151

Cc1ccccc1N(C)CCN

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.42
PRMT6 Q96LA8 1/20 0.42
PRMT8 Q9NR22 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
SIGMAR1 Q99720 1/20 0.40
NOTUM Q6P988 1/20 0.38
CYP3A4 P08684 2/20 0.38
LMNA P02545 2/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
AR P10275 1/20 0.37
ALDH1A1 P00352 2/20 0.37
TP53 P04637 2/20 0.37
ACHE P22303 2/20 0.36
TSHR P16473 1/20 0.36
HSD17B1 P14061 1/20 0.36
HSD17B2 P37059 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HTR7 P34969 1/20 0.35
SLC6A2 P23975 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18773862 0.86 ALDH1A1 (0.41) CARM1PRMT6PRMT8TAAR1SIGMAR1
SCHEMBL27650046 0.84 CARM1 (0.36) CARM1PRMT6PRMT8TAAR1LMNA
SCHEMBL18873158 0.83 NOTUM (0.38) TAAR1SIGMAR1NOTUMCYP3A4LMNA
SCHEMBL4601474 0.81 TAAR1 (0.43) CARM1PRMT6PRMT8TAAR1SIGMAR1
SCHEMBL5421931 0.81 TP53 (0.45) SIGMAR1NOTUMCYP3A4LMNATRPM8
SCHEMBL763820 0.81 AR (0.41) TAAR1NOTUMCYP3A4LMNATRPM8
SCHEMBL7255765 0.79 TP53 (0.44) SIGMAR1NOTUMCYP3A4LMNATRPM8
SCHEMBL11702654 0.79 ALDH1A1 (0.45) SIGMAR1NOTUMCYP3A4LMNATRPM8
SCHEMBL3871305 0.78 TSHR (0.43) SIGMAR1NOTUMCYP3A4LMNATRPM8
SCHEMBL5430493 0.78 ALDH1A1 (0.50) NOTUMCYP3A4LMNATRPM8ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6641804-B1 Resin and a diluent, the resin (T) providing a resin film having at least one resin selected from the group consisting of vinyl resins, polyester resins, polyamide resins, silicone resins, cationic urethane resins, ampholytic urethane resins SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2003-11-04 US disclosed
EP-1068859-A1 HAIR TREATMENT AND METHOD OF TREATING HAIR SANYO CHEMICAL INDUSTRIES, Ltd. (JP) 2001-01-17 EP disclosed